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Oxynitrilases (HNL)
Ku bijyanye na oxynitrilases
ES-HNLs: Enzyme yo mu rwego rwo hejuru itera imbaraga HCN kongeramo aldehydes (ketones) kugira ngo haboneke alcohols zo mu bwoko bwa R cyangwa S za cyanide, zishobora guhindurwa byoroshye ubwoko bwinshi bw'imiti cyangwa ibindi binyabutabire binyuze mu buryo bwa chimique.
Hari ubwoko 29 bw'ibicuruzwa bya oxynitrilase (Umubare nka ES-HNL-101～ES-HNL-129) byakozwe na SyncoZymes. SZ-HNL ni igikoresho cy'ingirakamaro mu guhuza uturere na stereo (R)-cyanohydrins cyangwa (S)-cyanohydrins biva mu bwoko butandukanye bwa aldehydes cyangwa se ketones zihumura neza, aliphatic na heterocyclic.
Ubwoko bw'ingaruka za "catalytic reaction":
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Nitro reductase (NTR)
Ku bijyanye no kugabanya imisemburo ya nitro
ES-NTRs: Ni enzymes za flavo zituma amatsinda ya nitro agabanuka bitewe na NAD (P)H bitewe n'ibinyabutabire bya nitro aromatic na nitroheterocyclic bijya kuri hydroxylamino na/cyangwa amino derivatives. Zikoreshwa cyane mu guhuza organic hydroxylamine na amine aromatic, kuvura kanseri, gupima ibinyabuzima no kwangiza imyuka ihumanya ibidukikije. Hari ubwoko 12 bwa Nitro reductase (NTR) products (Numero nka ES-NTR-101~ES-NTR-112) yakozwe na SyncoZymes.
Telefoni igendanwa/Wechat/WhatsApp: +86-13681683526
Imeri:lchen@syncozymes.com
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Aldolase (DERA)
ES-DERA: Ishobora gukurura neza uburyo bwo kongeramo ketone za donor kuri aldehydes za receptor. Byongeye kandi, uburyo bwo gukora bushobora gukorwa mu buryo bw'amazi bwa pH idafite aho ihuriye n'uburyo bwo kuyirinda. Ni iya aldolase yo mu cyiciro cya mbere, ikora Shiff base mu buryo bwa catalytic. Substrate ihuzwa neza n'itsinda rya amino ry'aho ikora kugira ngo itangire gucika no gushinga umugozi. Itandukaniro riri hagati ya DERAs n'izindi aldolases ni uko substrates zikoresha ari aldehydes kandi zishobora gukomeza gushonga kwa aldehydes.
Telefoni igendanwa/Wechat/WhatsApp: +86-13681683526
Imeri:lchen@syncozymes.com
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Cytochrome P450 monooxygenase (CYP)
Ku bijyanye na CYP
ES-CYPs: Ubwoko bwa enzymes za redox zifite mercaptan-heme nk'ikigo gikora mu gutuma ogisijeni ikwirakwizwa. Ni oxygenases za nyuma kandi zikenera heme kugira ngo ogisijeni ikoreshwe.
Cytochrome P450 monooxygenase itera ogisijeni, epoxidation na hydroxylation bya alkyl, hydroxylation na ogisijeni ya ammonia, ogisijeni ya sulfur, dealkylation (ogisijeni, sulfur, ammonia), ogisijeni yo gukuraho ogisijeni, deamination na dehalogenation.
Hari ubwoko 8 bw'ibicuruzwa bya monooxygenase bya cytochrome P450 (Umubare nka ES-CYP-101～ES-CYP-108) byakozwe na SyncoZymes.Telefoni igendanwa/Wechat/WhatsApp: +86-13681683526
Imeri:lchen@syncozymes.com
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Oxidase y'inzoga (AOX)
Ku bijyanye na oksidase y'inzoga
ES-AOXs: Izi enzymes zishobora gukurura ogisijeni ya alkoholi zirimo ibinure cyangwa aryl-alcohols kugira ngo zikore aldehydes. Zikoresha ogisijeni ya molekile ariko ntizikenera cofactor yongewemo inyuma, na peroxide ya hydrogen ikorwa.
Hari ubwoko butandatu bw'ibikomoka kuri okisidasi z'inzoga (Umubare nka ES-AOX-101~ES-AOX-106) byakozwe na SyncoZymes. ES-AOX101 na ES-AOX102 bikunda substrates za aliphatic alcohol, ES-AOX103~ ES-AOX105 bikunda substrates za aromatic alcohol, naho ES-AOX106 ikaba cholesterol oxidase. SZ-AOX ni igikoresho cy'ingirakamaro cyo gukurura okisidasi ya alcohol zirimo ibinure cyangwa aryl-alcohols kugira ngo ikore aldehydes.
Ubwoko bw'ingaruka za "catalytic reaction":
Telefoni igendanwa/Wechat/WhatsApp: +86-13681683526
Imeri:lchen@syncozymes.com
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D-Amino aside dehydrogenase (D-AADH)
Ku bijyanye na D-Amino aside dehydrogenase
ES-D-AADH (D-Amino aside dehydrogenase): enzyme ishobora kugabanya aside 2-keto muri aside D-amino ijyanye nayo. Igisubizo gikenera NADP(H) na amoniya idakora (nk'ammoniya cyangwa iyoni ya ammoniya). Hari ubwoko 17 bwa aside D-amino dehydrogenase (Umubare nka ES-DAADH-101~ ES-DAADH-117) bwakozwe na SyncoZymes.
Ubwoko bw'ingaruka za "catalytic reaction":
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Imeri:lchen@syncozymes.com
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Esterase na Lipase (PLE na CALB)
Ku bijyanye na Esterase na Lipase
ES-PLE: Ubwoko bwa hydrolases zituma habaho kandi zigacika burundu imigozi ya ester. Zishobora kugira uruhare mu buryo butandukanye bwo gukora ibintu bya shimi, nko gupima, guhindura imiterere y’ibinyabutabire mu mubiri no gupima imiterere y’ibinyabutabire. Zikoreshwa cyane mu nzego nyinshi nko gutunganya ibiribwa, inganda zikora imiti, ubuvuzi bw’ibinyabuzima, ubuvuzi bw’ibinyabutabire no kuvura ibidukikije.
Telefoni igendanwa/Wechat/WhatsApp: +86-13681683526
Imeri:lchen@syncozymes.com
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Epoxide hydrolase (EH)
Ku bijyanye na epoxide hydrolase
EH ni ether hydrolase itera hydrolysis ya stereoselective ya epoxides za racemic kugira ngo ikore 1, 2-diol na optique active epoxides, ishobora gukoreshwa mu gusubiza epoxides cyangwa gutegura chiral diols. Ikoreshwa cyane mu buvuzi no mu zindi nzego. Hari ubwoko butatu bw'ibicuruzwa bya epoxide hydrolases (Umubare nka ES-EH-101～ES-EH-103) byakozwe na SyncoZymes. ES-EH ni igikoresho cy'ingirakamaro cyo gutera imikorere ya chiral alcohols binyuze muri stereoselective hydrolysis ya aliphatic na aromatic epoxides.
Ubwoko bw'ingaruka za "catalytic reaction":
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Imeri:lchen@syncozymes.com
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Formate dehydrogenase (FDH)
Ku bijyanye na Formate dehydrogenase
ES-FDH (Formate dehydrogenase): FDH itera imbaraga zo gukuraho umwuka wa ammonium formate kugira ngo ikore dioxyde de carbone na ammonia, kandi igatuma NAD iba NADH hamwe na NAD nk'igikoresho cya elegitoroniki. FDH ikunze gukoreshwa mu kuvugurura coenzyme NADH. Hari ubwoko bune bw'ibicuruzwa bya enzyme ya FDH (ES-FDH-101~ES-FDH-104) byakozwe na SyncoZymes, muri byo ES-FDH102 ifite imikorere myinshi kandi niyo FDH isabwa cyane.
Ubwoko bw'ingaruka za "catalytic reaction":
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Imeri:lchen@syncozymes.com
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Glucose dehydrogenase (GDH)
Ku bijyanye na glucose dehydrogenase
ES-GDH (Glucose dehydrogenase): GDH itera imbaraga mu gukuraho glucose mu mubiri kugira ngo ikore aside gluconic (lactone), kandi igagabanya NAD(P)+ ikaba NAD(P)H, NAD(P)+ ikaba electron receptor. GDH ikunze gukoreshwa mu kuvugurura coenzyme NAD(P)H mu mirima ya biocatalysis hamwe n'indi enzyme nyamukuru. Hari ubwoko 10 bw'ibicuruzwa bya enzymes za GDH (ES-GDH-101~ES-GDH-110) byakozwe na SyncoZymes, muri byo ES-GDH110 ifite imikorere myinshi kandi niyo GDH isabwa cyane.
Ubwoko bw'ingaruka za "catalytic reaction":
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Imeri:lchen@syncozymes.com
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Monoamine oxidase (MAO)
Ku bijyanye na Monoamine oxidase
ES-MAO (Monoamine oxidase): MAO itera ogisijeni mu gukuraho ogisijeni muri monoamines kugira ngo ikore peroxide ya hydrogen, ammonia na aldehydes bijyana nayo. Mu nzira ya catalytic, ogisijeni ni ngombwa nk'umusemburo. Hari ubwoko 6 bw'ibicuruzwa bya enzymes za MAO (Umubare nka ES-MAO-101～ES-MAO-106) byakozwe na SyncoZymes, bishobora gukoreshwa mu gukuraho ogisijeni mu bintu bya monoamine.
Ubwoko bw'ingaruka za "catalytic reaction":
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Imeri:lchen@syncozymes.com
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Lactate Dehydrogenase (LDH)
Ku bijyanye na Lactate dehydrogenase
Hari ubwoko bumwe bw'umusaruro wa enzyme ya LDH (Numero nka ES-LDH) yakozwe na SyncoZymes. LDH ishobora gutuma pyruvate igabanuka ikaba aside L-lactic, cyangwa ikagabanya izindi aside α-keto zisa nazo. Mu gihe cyo gukatalisa, NADH irakenewe nk'umuyoboro wa hydrogen.
Ubwoko bw'ingaruka za Lactate dehydrogenasecatalytic
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