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Ketoreductase (KRED)
Ibyerekeye Ketoreductase
Enzymes: Nibintu bya macromolecular biologiya, imisemburo myinshi ni proteyine.
Ketoreductase: Nanone yitwa "Carbonyl reductase", ni enzymes zitera reaction ya redox reaction hagati ya aldehydes / ketone na alcool, kandi ikenera coenzymes nka transmitter ya H nka NADH cyangwa NADPH.Hariho ibyiciro bitatu byingenzi bya KRED: Urunigi rugufi Dehydrogenase / Kugabanya (SDRs), Urunigi rwo hagati rwa Dehydrogenase / Kugabanya (MDRs), na Aldo-KetoReductases (AKRs).Imikorere ya catalitiki ya batatu irasa, ariko imiterere nimiterere biratandukanye.
Terefone / Wechat / WhatsApp: + 86-13681683526
E-Mail:lchen@syncozymes.com
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Transaminase (ATA)
Ibyerekeye transaminase
ATA yo muri SyncoZymes: Hariho ubwoko 66 bwibicuruzwa bya enzyme ya ATA (Umubare nka ES-ATA-101 ~ ES-ATA-166) byakozwe na SyncoZymes.SZ-ATA nigikoresho cyingirakamaro muguhindura synthesis ya regio- na stereoselective synthesis ya chiral amine, acide amino hamwe nibikomoka kuri ketoacide zitandukanye za alifatique na aromatic, aldehydes, ketone na ketose.
Terefone / Wechat / WhatsApp: + 86-13681683526
E-Mail:lchen@syncozymes.com
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Nitrilase (NIT)
Ibyerekeye Nitrilase
ES-NITs: Hindura mu buryo butaziguye itsinda rya cyanide mu itsinda rya carboxyl, kugirango utegure aside irike, ikoreshwa cyane mu buvuzi, kurengera ibidukikije, inganda z’imiti, inyongeramusaruro, imyenda, umusaruro w’ubuhinzi n’izindi nzego.
Hariho ubwoko 40 bwibicuruzwa bya Nitrilase (NIT) (Umubare nka ES-NIT-101 ~ ES-NIT-140) byakozwe na SyncoZymes.ES-NIT nigikoresho cyingirakamaro muguhindura synthesis ya chiral carboxylic acide ikoresheje hydrolysis ya regio- na stereoselective hydrolysis ya nitrile ya alifatique na aromatic.Ubwoko bwa catalitiki yerekana:
Terefone / Wechat / WhatsApp: + 86-13681683526
E-Mail:lchen@syncozymes.com
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Nitrile hydratase (NHT)
Ibyerekeye ES-NHTs
ES-NHTs: icyiciro cya metalloenzyme, ihitamo nitrile ihitamo amide yibanze ihuye.Ntabwo zikoreshwa cyane muguhuza aside aside amine, amide, acide karubike na aside ikomokaho, ariko no mugutegura imiti ya chiral.Hariho ubwoko 24 bwa nitrile hydratase yakozwe na SyncoZymes (Umubare nka ES-NHT-101 ～ ES-NHT-124).
Ubwoko bwa catalitiki yerekana:
Terefone / Wechat / WhatsApp: + 86-13681683526
E-Mail:lchen@syncozymes.com
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Amidase (AMD)
AMD yo muri SyncoZymes: Hariho ubwoko 19 bwibicuruzwa bya enzyme ya AMD (Umubare nka ES-AMD-101 ~ ES-AMD-119) byakozwe na SyncoZymes.SZ-AMD nigikoresho cyingirakamaro muguhindura synthesis ya regio- na stereoselective synthesis ya chiral carboxylic acide nibibikomoka kuri amide itandukanye ya alifatique na aromatic.
Terefone / Wechat / WhatsApp: + 86-13681683526
E-Mail:lchen@syncozymes.com
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Ene reductase (ERED)
Ibyerekeye ene reductase
ES-EREDs: Mumuryango wumusemburo ushaje wumuhondo ugabanya guhitamo C = C muri α, β -ibintu bituzuye hamwe nitsinda rikurura electron.Zikoreshwa cyane mubushakashatsi bwibikomoka kuri aside amine, ibintu bioaktike, abahuza imiti, ibirungo hamwe na chiral.
Terefone / Wechat / WhatsApp: + 86-13681683526
E-Mail:lchen@syncozymes.com
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Oxynitrilase (HNL)
Ibyerekeye oxynitrilase
ES-HNLs: Enzyme yo mu rwego rwa enantioselectively ituma hiyongeraho HCN kuri aldehydes (ketone) kugirango ibone alcool yo mu bwoko bwa R cyangwa S, ishobora guhinduka muburyo butandukanye bwibiyobyabwenge cyangwa abahuza ibiyobyabwenge hakoreshejwe uburyo bwa chimique.
Hariho ubwoko 29 bwibicuruzwa bya oxynitrilase (Umubare nka ES-HNL-101 ～ ES-HNL-129) byakozwe na SyncoZymes.SZ-HNL nigikoresho cyingirakamaro kuri regio- na stereo- guhitamo synthesis ya (R) -cyanohydrins cyangwa (S) -cyanohydrins biva muburyo butandukanye bwa aromatic, aliphatic na heterocyclic aldehydes cyangwa na ketone.
Ubwoko bwa catalitiki yerekana:
Terefone / Wechat / WhatsApp: + 86-13681683526
E-Mail:lchen@syncozymes.com
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Nitro reductase (NTR)
Kubijyanye na nitro reductase
ES-NTRs: Ese flavoenzymes itera kugabanya NAD (P) H iterwa no kugabanuka kwamatsinda ya nitro kuri nitroaromatic na nitroheterocyclic ivanze na hydroxylamino na / cyangwa ibikomoka kuri amino.Zikoreshwa cyane muri synthesis organic ya hydroxylamine ya aromatic na amine aromatic, kuvura ibibyimba, gutahura ibinyabuzima no kwangiza ibidukikije.Hariho ubwoko 12 bwibicuruzwa bya Nitro (NTR) (Umubare nka ES-NTR-101 ~ ES-NTR-112) byakozwe na SyncoZymes.
Terefone / Wechat / WhatsApp: + 86-13681683526
E-Mail:lchen@syncozymes.com
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Aldolase (DERA)
ES-DERAs: Irashobora guhagarika neza stereoselective yongeyeho ketone yabaterankunga kuri reseptor aldehydes.Byongeye kandi, reaction irashobora gukorwa mugisubizo cyamazi ya pH idafite aho ibogamiye nta ngamba zidasanzwe zo gukingira.Biri mucyiciro cya I aldolase, ikora Shiff base mubikorwa bya catalitiki.Substrate ihujwe hamwe na amino itsinda ryurubuga rukora kugirango itangire gucika no gushinga ubumwe.Itandukaniro riri hagati ya DERAs nizindi aldolase nuko insimburangingo zitanga ari aldehydes kandi zishobora gukurikiranwa na aldehydes ikomeza.
Terefone / Wechat / WhatsApp: + 86-13681683526
E-Mail:lchen@syncozymes.com
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Cytochrome P450 monooxygenase (CYP)
Ibyerekeye CYP
ES-CYPs: Urwego rwimisemburo ya redox hamwe na mercaptan-heme nkikigo gikora kugirango uhindure ogisijeni.Ni okisijene ya terminal kandi ikenera heme kugirango ikore ogisijeni.
Cytochrome P450 monooxygenase itera okiside, epoxidation na hydroxylation ya alkyl, hydroxylation na okiside ya ammonia, okiside ya sulfure, dealkylation (ogisijeni, sulfure, amoniya), okiside dehydrogenation, deamination na dehalogenation.
Hariho ubwoko 8 bwibicuruzwa bya cytochrome P450 monooxygenase (Umubare nka ES-CYP-101 ～ ES-CYP-108) byakozwe na SyncoZymes.Terefone / Wechat / WhatsApp: + 86-13681683526
E-Mail:lchen@syncozymes.com
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Okiside ya alcool (AOX)
Ibyerekeye okiside ya alcool
ES-AOXs: Iyi misemburo irashobora guhagarika okiside ya alcool yuzuye amavuta cyangwa aryl-alcool kugirango ibe aldehydes.Bakoresha ogisijeni ya molekile ariko ntibisaba cofactor yongeyeho hanze, na hydrogen peroxide yakozwe.
Hariho ubwoko 6 bwibicuruzwa bya alcool (Umubare nka ES-AOX-101 ~ ES-AOX-106) byakozwe na SyncoZymes.ES-AOX101 na ES-AOX102 bahitamo ibinyobwa bisindisha bya alifatique, ES-AOX103 ~ ES-AOX105 bahitamo ibinyobwa bisindisha, naho ES-AOX106 ni okiside ya cholesterol.SZ-AOX nigikoresho cyingirakamaro muguhagarika okiside ya alcool yibinure cyangwa aryl-alcool kugirango itange aldehydes.
Ubwoko bwa catalitiki yerekana:
Terefone / Wechat / WhatsApp: + 86-13681683526
E-Mail:lchen@syncozymes.com
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D-Amino aside dehydrogenase (D-AADH)
Ibyerekeye aside D-Amino dehydrogenase
ES-D-AADH (D-Amino aside dehydrogenase): enzyme ishobora kugabanya aside 2-keto muri aside D-amino ihuye.Igisubizo gikeneye NADP (H) hamwe n’umuterankunga wa ammonia (nka ammonia cyangwa ion amonium).Hariho ubwoko 17 bwa D-amino acide dehydrogenase (Umubare nka ES-DAADH-101 ~ ES-DAADH-117) wakozwe na SyncoZymes.
Ubwoko bwa catalitiki yerekana:
Terefone / Wechat / WhatsApp: + 86-13681683526
E-Mail:lchen@syncozymes.com
