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Transaldolase (TAL)
Ibyerekeye Transaldolase
ES-TAL (Transaldolase): ahanini yerekeza kuri threonine transaldolases, ishobora gukurura uburyo bwo gukora ibikomoka kuri β-hydroxyphenylalanine hamwe n'ibikomoka kuri threonine na benzaldehyde. TAL ni enzyme ishingiye kuri PLP. Hari ubwoko bumwe gusa bw'ibikomoka kuri enzyme ya TAL (Umubare nka ES-TAL101) byakozwe na SyncoZymes, bishobora gukoreshwa mu gukora β-hydroxyphenylalanine n'ibikomoka kuri yo.
Ubwoko bw'ingaruka za "catalytic reaction":
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Ketoreductase (KRED)
Ku bijyanye na Ketoreductase
Enzymes: Ni catalysts za macromolecular biological, enzymes nyinshi ni poroteyine.
Ketoreductase: Nanone yitwa "Carbonyl reductase", ni enzymes zihindura redox reaction hagati ya aldehydes / ketones na alcohols, kandi zikenera coenzymes nk'umuyoboro wa H nka NADH cyangwa NADPH. Hari ibyiciro bitatu by'ingenzi bya KRED: Short-chain Dehydrogenase / Reductases (SDRs), Medium-chain Dehydrogenases / Reductases (MDRs), na Aldo-KetoReductases (AKRs). Imikorere ya catalytic ya bitatu irasa, ariko imiterere n'imiterere biratandukanye cyane.
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Imeri:lchen@syncozymes.com
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Transaminase (ATA)
Ku bijyanye na transaminase
ATA ikomoka kuri SyncoZymes: Hari ubwoko 66 bw'ibicuruzwa bya enzyme ya ATA (Umubare nka ES-ATA-101~ES-ATA-166) byakozwe na SyncoZymes. SZ-ATA ni igikoresho cy'ingirakamaro cyo gukurura imiterere ya chiral amines, aside amines n'ibikomoka kuri zo bivuye mu bwoko butandukanye bwa aliphatic na aromatic ketoacides, aldehydes, ketones na ketoses.
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Imeri:lchen@syncozymes.com
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Nitrilase (NIT)
Ibyerekeye Nitrilase
ES-NITs: Guhindura itsinda rya cyanide mu itsinda rya carboxyl, kugira ngo hategurwe aside carboxylic, ikoreshwa cyane mu buvuzi, kurengera ibidukikije, inganda z'imiti, inyongeramusaruro z'ibiribwa, imyenda, umusaruro w'ubuhinzi n'ibindi bikorwa.
Hari ubwoko 40 bw'ibicuruzwa bya Nitrilase (NIT) (Umubare nka ES-NIT-101~ES-NIT-140) byakozwe na SyncoZymes. ES-NIT ni igikoresho cy'ingirakamaro cyo gushishikariza ikorwa rya aside carboxylic chiral binyuze muri hydrolysis ya regio- na stereoselective ya nitriles nyinshi za aliphatic na aromatic.Ubwoko bw'ingaruka za "catalytic reaction":
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Imeri:lchen@syncozymes.com
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Nitrile hydratase (NHT)
Ku bijyanye na ES-NHTs
ES-NHTs: ubwoko bwa metalloenzyme, butuma nitriles zihinduka mu buryo bwihariye muri amide y'ibanze ijyanye nayo. Zikoreshwa cyane atari mu gukora aside amine, aside karbokisilike n'ibikomoka kuri zo gusa, ahubwo no mu gutegura imiti ya chiral. Hari ubwoko 24 bwa nitrile hydratases zakozwe na SyncoZymes (Umubare nka ES-NHT-101～ES-NHT-124).
Ubwoko bw'ingaruka za "catalytic reaction":
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Amidase (AMD)
AMD ikomoka kuri SyncoZymes: Hari ubwoko 19 bw'ibicuruzwa bya enzyme bya AMD (Umubare nka ES-AMD-101~ES-AMD-119) byakozwe na SyncoZymes. SZ-AMD ni igikoresho cy'ingirakamaro cyo gukurura imiterere ya aside karubokisilike ya chiral n'ibikomoka kuri yo bivuye mu bwoko butandukanye bwa alifatique na aromatique.
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Imeri:lchen@syncozymes.com
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Ene reductase (ERED)
Ku bijyanye na ene reductase
ES-ERED: Ziri mu muryango w'imisemburo ishaje y'umuhondo igabanya C=C mu buryo bwihariye mu bintu α, β-unsaturated hamwe n'amatsinda akura electron. Zikoreshwa cyane mu bushakashatsi ku bintu bikomoka kuri aside amine, ibintu bikora ku buzima, imiti ikoreshwa mu buvuzi, ibirungo n'ibice bya chiral.
Telefoni igendanwa/Wechat/WhatsApp: +86-13681683526
Imeri:lchen@syncozymes.com
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Oxynitrilases (HNL)
Ku bijyanye na oxynitrilases
ES-HNLs: Enzyme yo mu rwego rwo hejuru itera imbaraga HCN kongeramo aldehydes (ketones) kugira ngo haboneke alcohols zo mu bwoko bwa R cyangwa S za cyanide, zishobora guhindurwa byoroshye ubwoko bwinshi bw'imiti cyangwa ibindi binyabutabire binyuze mu buryo bwa chimique.
Hari ubwoko 29 bw'ibicuruzwa bya oxynitrilase (Umubare nka ES-HNL-101～ES-HNL-129) byakozwe na SyncoZymes. SZ-HNL ni igikoresho cy'ingirakamaro mu guhuza uturere na stereo (R)-cyanohydrins cyangwa (S)-cyanohydrins biva mu bwoko butandukanye bwa aldehydes cyangwa se ketones zihumura neza, aliphatic na heterocyclic.
Ubwoko bw'ingaruka za "catalytic reaction":
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Nitro reductase (NTR)
Ku bijyanye no kugabanya imisemburo ya nitro
ES-NTRs: Ni enzymes za flavo zituma amatsinda ya nitro agabanuka bitewe na NAD (P)H bitewe n'ibinyabutabire bya nitro aromatic na nitroheterocyclic bijya kuri hydroxylamino na/cyangwa amino derivatives. Zikoreshwa cyane mu guhuza organic hydroxylamine na amine aromatic, kuvura kanseri, gupima ibinyabuzima no kwangiza imyuka ihumanya ibidukikije. Hari ubwoko 12 bwa Nitro reductase (NTR) products (Numero nka ES-NTR-101~ES-NTR-112) yakozwe na SyncoZymes.
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Imeri:lchen@syncozymes.com
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Aldolase (DERA)
ES-DERA: Ishobora gukurura neza uburyo bwo kongeramo ketone za donor kuri aldehydes za receptor. Byongeye kandi, uburyo bwo gukora bushobora gukorwa mu buryo bw'amazi bwa pH idafite aho ihuriye n'uburyo bwo kuyirinda. Ni iya aldolase yo mu cyiciro cya mbere, ikora Shiff base mu buryo bwa catalytic. Substrate ihuzwa neza n'itsinda rya amino ry'aho ikora kugira ngo itangire gucika no gushinga umugozi. Itandukaniro riri hagati ya DERAs n'izindi aldolases ni uko substrates zikoresha ari aldehydes kandi zishobora gukomeza gushonga kwa aldehydes.
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Imeri:lchen@syncozymes.com
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Cytochrome P450 monooxygenase (CYP)
Ku bijyanye na CYP
ES-CYPs: Ubwoko bwa enzymes za redox zifite mercaptan-heme nk'ikigo gikora mu gutuma ogisijeni ikwirakwizwa. Ni oxygenases za nyuma kandi zikenera heme kugira ngo ogisijeni ikoreshwe.
Cytochrome P450 monooxygenase itera ogisijeni, epoxidation na hydroxylation bya alkyl, hydroxylation na ogisijeni ya ammonia, ogisijeni ya sulfur, dealkylation (ogisijeni, sulfur, ammonia), ogisijeni yo gukuraho ogisijeni, deamination na dehalogenation.
Hari ubwoko 8 bw'ibicuruzwa bya monooxygenase bya cytochrome P450 (Umubare nka ES-CYP-101～ES-CYP-108) byakozwe na SyncoZymes.Telefoni igendanwa/Wechat/WhatsApp: +86-13681683526
Imeri:lchen@syncozymes.com
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Oxidase y'inzoga (AOX)
Ku bijyanye na oksidase y'inzoga
ES-AOXs: Izi enzymes zishobora gukurura ogisijeni ya alkoholi zirimo ibinure cyangwa aryl-alcohols kugira ngo zikore aldehydes. Zikoresha ogisijeni ya molekile ariko ntizikenera cofactor yongewemo inyuma, na peroxide ya hydrogen ikorwa.
Hari ubwoko butandatu bw'ibikomoka kuri okisidasi z'inzoga (Umubare nka ES-AOX-101~ES-AOX-106) byakozwe na SyncoZymes. ES-AOX101 na ES-AOX102 bikunda substrates za aliphatic alcohol, ES-AOX103~ ES-AOX105 bikunda substrates za aromatic alcohol, naho ES-AOX106 ikaba cholesterol oxidase. SZ-AOX ni igikoresho cy'ingirakamaro cyo gukurura okisidasi ya alcohol zirimo ibinure cyangwa aryl-alcohols kugira ngo ikore aldehydes.
Ubwoko bw'ingaruka za "catalytic reaction":
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