Aldolase (DERA)

Ibisobanuro bigufi:

ES-DERAs: Irashobora guhagarika neza stereoselective yongeyeho ketone yabaterankunga kuri reseptor aldehydes.Byongeye kandi, reaction irashobora gukorwa mugisubizo cyamazi ya pH idafite aho ibogamiye nta ngamba zidasanzwe zo gukingira.Biri mucyiciro cya I aldolase, ikora Shiff base mubikorwa bya catalitiki.Substrate ihujwe hamwe na amino itsinda ryurubuga rukora kugirango itangire gucika no gushinga ubumwe.Itandukaniro riri hagati ya DERAs nizindi aldolase nuko insimburangingo zitanga ari aldehydes kandi zishobora gukurikiranwa na aldehydes ikomeza.

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Ibicuruzwa birambuye

Ibicuruzwa

Ibyerekeye Aldolase:

Hariho ubwoko 8 bwibicuruzwa bya aldolase (Umubare nka ES-DERA-101 ～ ES-DERA-108) byakozwe na SyncoZymes.SZ-DERA nigikoresho cyingirakamaro muguhindura enantioselective karubone-karubone ihuza, itanga ibigo bigera kuri bibiri bya chiral mubihe byoroheje.

Ubwoko bwa catalitiki yerekana:

Uburyo bwa Catalitike:

Amakuru y'ibicuruzwa:

Enzymes	Kode y'ibicuruzwa	Ibisobanuro
Ifu ya Enzyme	ES-DERA-101 ~ ES-DERA-108	urutonde rwa 8 Aldolase, 50 mg buri kintu 8 * 50mg / ikintu, cyangwa ibindi byinshi
Igikoresho cyo kwerekana (SynKit)	ES-DERA-800	urutonde rwa 8 Aldolase, 1 mg buri kintu 8 * 1mg / ikintu

Ibyiza:

★ Kugura ibintu byinshi.
Guhindura byinshi.
Ibicuruzwa bike.
Conditions Imiterere yoroheje.
Yangiza ibidukikije.

Amabwiriza yo gukoresha:

Ally Mubisanzwe, sisitemu yo kwitwara igomba kuba irimo substrate, igisubizo cya buffer (reaction nziza pH) na ES-DERA.
Ubwoko bwose bwa ES-DERAs bujyanye nuburyo bwiza bwo kwitwara bugomba kwigwa kugiti cye.
ES ES-DERA igomba kongerwaho nyuma muri sisitemu yo kwitwara kugirango ikomeze ibikorwa.
Kwibanda cyane Substrate cyangwa ibicuruzwa hamwe bishobora kubuza ibikorwa bya ES-DERA.Ariko, kubuzwa birashobora koroherezwa mugice cyo kongeramo substrate.