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Imine reductase (IRED)
Kubijyanye na Imine reductase
ES-IRED: Urwego rwa enzymes zituma igabanuka rya C = N ihuza CN.Nibya redox enzyme, hamwe na coenzyme NADPH yo gutwara hydrogen.Ukurikije chiral ikunda ibicuruzwa, birashobora kugabanywa R-IRED na S-IRED.Syncozymes yateje imbere imine 15 (numbIRED ES-IRED-101-ES-IRED-115), ishobora gukoreshwa cyane mukugabanya regioselective na stereoselective kugabanya imine kugirango bategure amine ya chiral.
Ubwoko bwa catalitiki yerekana:
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E-Mail:lchen@syncozymes.com
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Reditase ya Nitrile (NRED)
Kubijyanye na reditase ya Nitrile
Hariho ubwoko 3 bwibicuruzwa bya NRED enzyme (Umubare nka ES-NRED101 ~ ES-NRED103) byakozwe na SyncoZymes.NRED irashobora kugabanya kugabanuka kwa groupe nitrile kuri amine.Mubikorwa bya catalizike, NADPH irakenewe nkabatwara hydrogen.
Ubwoko bwa Nitrile reductasecatalytic reaction
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E-Mail:lchen@syncozymes.com
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Phenylalanine dehydrogenase (PDH)
Ibyerekeye Phenylalanine dehydrogenase
ES-PDH: Icyiciro cya oxydeore.Imyitwarire myiza irashobora gutuma okiside yangiza umunyu wa L fenylalanine imbere ya NAD kugirango itange umunyu wa fenylpyruvate, kandi reaction irashobora guhinduka muguhindura umunyu wa aside amine uva mumunyu wa fenylpyruvate.Syncozymes yateje imbere ibintu 8 bya fenylalanine dehydrogenase (ifite numero ES-PDH-101 ~ ES-PDH-108).ES-PDH irashobora gukoreshwa mugutegura umunyu wa fenylalanine cyangwa umunyu wa aside amine uva mumunyu wa acide ya fenylpyruvic cyangwa ibikomoka.
Ubwoko bwa catalitiki yerekana:
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E-Mail:lchen@syncozymes.com
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Leucine Dehydrogenase (LeuDH)
Ibyerekeye Leucine dehydrogenase
Hariho ubwoko 1 bwibicuruzwa bya LeuDH enzyme (Umubare nka ES-LeuDH-101) byakozwe na SyncoZymes.LeuDH irashobora guhagarika ammoniation ya aside ya methylbutanoic 4 (umunyu) kuri L-leucine cyangwa okiside ya leucine kuri acide 4-methylbutanoic.ES-LeuDH irashobora kandi guhagarika aminide igabanya aside α-keto ifite imiterere isa nogutegura ibikomoka kuri aside amine.Mubikorwa bya catalizike, NADH irakenewe nkabatwara hydrogen.
Ubwoko bwa reaction ya Leucine dehydrogenasecatalytic
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E-Mail:lchen@syncozymes.com
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Threonine deaminase (TDA)
Ibyerekeye Threonine deaminase
ES-TDA (Threonine deaminase): poroteyine ya pyridoxal fosifate itera kwanduza threonine kugirango itange aside 2-ketobutyric na ammonia.Pyridoxal 5-fosifate irakenewe nka coenzyme muri sisitemu ya catalitiki.Hariho ubwoko 1 gusa bwibicuruzwa bya TDA enzyme (Umubare nka ES-TDA) byakozwe na SyncoZymes, bishobora gukoreshwa mugutegura aside 2-ketobutyric cyangwa ibikomoka kuri threonine.
Ubwoko bwa catalitiki yerekana:
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E-Mail:lchen@syncozymes.com
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Amine Dehydrogenase (AmDH)
Ibyerekeye Amine Dehydrogenase
ES-AmDH (Amine Dehydrogenase): enzyme ishobora guhagarika ammoniation yitsinda rya karubone ikayigabanya mumatsinda ya amino.Ni coenzyme NADH iterwa na enzyme, kandi NADH ikora nka hydrogène yohereza.Hariho ubwoko 4 bwibicuruzwa bya enzyme ya AmDH (Umubare nka ES-AmDH101 ～ ES-AmDH104) byakozwe na SyncoZymes, bishobora gukoreshwa muri regioselective cyangwa stereoselective reductive amination ya aldehydes na ketone.
Ubwoko bwa catalitiki yerekana:
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E-Mail:lchen@syncozymes.com
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Nucloside fosifora (NP)
Ibyerekeye nucleoside fosifora
Hariho ubwoko 3 bwibicuruzwa bya NP enzyme (Umubare nka ES-NP-101 ~ ES-NP-103) byakozwe na SyncoZymes.ES-NP-101 ni purine nucleoside fosifora, ES-NP-102 na ES-NP-103 ni pyrimidine nucleoside fosifori.Nucleosidephosphorylase irashobora kubora nucleoside mubice na fosifate ya pentose.Nucleoside phosphorylase irashobora kugabanywamo purine nucleoside fosifora na pyrimidine nucleoside phosphorylase ukurikije ibyifuzo bya nucleoside.Posine nucleoside fosifora irashobora guhinduranya adenosine kuri adenine, inosine kuri hypoxanthine, guanosine kuri guanine, kandi ikabyara fosifate ya ribose icyarimwe.Pyrimidine nucleoside fosifora irashobora guhinduranya uridine kuri uracil kandi ikabyara fosifate ya ribose.
Terefone / Wechat / WhatsApp: + 86-13681683526
E-Mail:lchen@syncozymes.com
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Hydroaminase (HAM)
Ibyerekeye Hydroaminase
Hariho ubwoko 2 bwibicuruzwa bya HAM enzyme (Umubare nka ES-HAM-101 ~ ES-HAM-102) byakozwe na SyncoZymes.HAM irashobora guhagarika ammoniation ya acide enoic cyangwa ibiyikomokaho kugirango ikore aside chiral amino.HAM irashobora gukoreshwa mugushushanya chiral amino acide (cyangwa chiral amine) ivuye muri acide enoic (cyangwa alkenes).Umuterankunga wa Amoniya, nk'amazi ya amoniya cyangwa umunyu wa amonium, birakenewe.
Ubwoko bwa Hydroaminase catalitike yubwoko
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E-Mail:lchen@syncozymes.com
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CALB yimuwe
CALB
Recombinant Lipase B yo muri Candida antarctica (CALB) ikorwa na fermentation yarohamye hamwe na pasitori ya Pichia yahinduwe.
CALB irashobora gukoreshwa mugice cyamazi cyangwa icyiciro cya catalitiki esterifike, esterolysis, transesterifike, impeta ifungura polyester synthesis, aminolysis, hydrolysis ya amide, acylation ya amine hamwe ninyongera.
CALB hamwe no guhitamo chiral nyinshi no guhitamo imyanya, bityo irashobora gukoreshwa cyane mugutunganya amavuta, ibiryo, ubuvuzi, kwisiga nizindi nganda zikora imiti.
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E-Mail:lchen@syncozymes.com
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NADH oxydease (NOX)
Ibyerekeye okiside ya NADH
ES-NOX (NADH oxydease): NOX itera okiside ya NADH kuri NAD +, kandi ni iya oxydeore.Muburyo bwa okiside, O2 irakenewe nka okiside, kandi igabanuka kuri H2O cyangwa H2O2.Hariho ubwoko 4 bwibicuruzwa bya enzyme ya NOX (ES-NOX-101 ~ ES-NOX-104) byakozwe nisosiyete yacu, bishobora gukoreshwa muguhindura okiside ya coenzyme NAD +.
Ubwoko bwa catalitiki yerekana:
or
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E-Mail:lchen@syncozymes.com
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Phenylalanine ammonia lyase (PAL)
Ibyerekeye Phenylalanine ammonia lyase
ES-PAL: Icyiciro cyimisemburo itera kwanduza L-phenylalanine itaziguye kuri acide transinnamic.Syncozymes yateje imbere ibintu 10 bya fenylalanine ammonia lyase (inomero ya ES-PAL-101 ~ ES-PAL-110), ishobora gukoreshwa mugusenya cyangwa gusubiza inyuma fenilalanine n'ibiyikomokaho.
Ubwoko bwa catalitiki yerekana:
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E-Mail:lchen@syncozymes.com
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Catalase (CAT)
Ibyerekeye Catalase
ES-CAT (Catalase): itera kubora kwa H2O2 muri ogisijeni n'amazi.Bibaho cyane cyane muri mitochondriya, reticulum ya endoplasmeque, umwijima winyamanswa hamwe ningirangingo zamaraso zitukura, cyane cyane mwumwijima mwinshi cyane, bitanga umubiri wo kwirinda antioxydeant kumubiri.Muri biocatalyse, ikoreshwa cyane cyane mugukuraho reaction ya hydrogène peroxide yibicuruzwa no kugabanya kubuza no kudakora enzyme na hydrogen peroxide.Hariho ubwoko 1 gusa bwibicuruzwa bya CAT enzyme byakozwe na SyncoZymes (Umubare nka ES-CAT).
Ubwoko bwa catalitiki yerekana:
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E-Mail:lchen@syncozymes.com
