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Phosphokinase (PKase)
Ku bijyanye na Phosphokinase
ES-PKase (Phosphokinase): itera imbaraga mu kohereza amatsinda ya fosfeti kuri ATP mu bindi bintu. Itera imbaraga kandi mu kohereza amatsinda ya fosfeti ku zindi nucleoside za triphosphate rimwe na rimwe. Inyinshi muri kinase zikenera iyoni z'icyuma zivanze kugira ngo zigire uruhare mu gikorwa (muri rusange Mg2+). Hari ubwoko 21 bw'ibicuruzwa bya enzyme ya PKase (Umubare nka ES-PKase101~ ES-PKase-121) byakozwe na SyncoZymes.
Ubwoko bw'ingaruka za "catalytic reaction":
Telefoni igendanwa/Wechat/WhatsApp: +86-13681683526
Imeri:lchen@syncozymes.com
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Cyclooxygenase (COX)
Ku bijyanye na Cyclooxygenase
ES-COX (Cyclooxygenase): ihindura imiyoboro ya C=C muri epoxide. Hari ubwoko 11 bw'ibicuruzwa bya enzyme ya COX (Umubare nka ES-COX101~ ES-COX-111) byakozwe na SyncoZymes. Dukurikije uburyo butandukanye bwo gukaranga, COX ya SyncoZymes igabanyijemo haloperoxidase na styrene monooxygenase. ES-COX101, 102, 107-111 igize haloperoxidase, mu gihe ES-COX103-106 igize styrene monooxygenase.
Telefoni igendanwa/Wechat/WhatsApp: +86-13681683526
Imeri:lchen@syncozymes.com
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Cyclohexanone monooxygenase (CHMO)
Ku bijyanye na Cyclohexanone monooxygenase
ES-CHMO (Cyclohexanone monooxygenase): Baeyer Villiger monooxygenase (BVMO) hamwe na cyclohexanone nk'umusemburo, ishobora kohereza cyclohexanone muri cyclohexanol ikoresheje ogisijeni.
Ni ubwoko bwa enzyme ishingiye kuri flavin. Flavin ya oxidized igabanuka ikaba flavin mu gihe cyo kugabanya coenzyme II (NADPH) kugira ngo habeho oxidation itaha. Kubwibyo, cofactor NADPH ni ngombwa mu gihe cya flavin. Hari ubwoko bumwe gusa bwa enzyme ya CHMO (Umubare nka ES-CHMO101) yakozwe na SyncoZymes, ishobora gukoreshwa mu gukurura cyclohexanone muri cyclohexanone.
Ubwoko bw'ingaruka za "catalytic reaction":
Telefoni igendanwa/Wechat/WhatsApp: +86-13681683526
Imeri:lchen@syncozymes.com
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Kugabanya aside karubokisilike (CAR)
Ku bijyanye no kugabanya aside karubokisilike
ES-CAR (aside carboxylic reductase): itera imbaraga kugabanya itsinda rya carboxyl rijya muri aldehyde. Mu nzira ya catalytic, ATP activation na coenzyme NADPH ni byo bikenewe nk'ibitwara hydrogen. Hari ubwoko bubiri bw'ibicuruzwa bya enzymes za CAR (Umubare nka ES-CAR101~ ES-CAR-102) byakozwe na SyncoZymes.
Ubwoko bw'ingaruka za "catalytic reaction":
Telefoni igendanwa/Wechat/WhatsApp: +86-13681683526
Imeri:lchen@syncozymes.com
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Eluxadoline Methyl Intermediate 5-(((S)-2-((tert-butoxycarbonyl)amino)-3-(4-carbamoyl-2,6-dimethylphenyl)-N-((S)-1-(4-phenyl-1H-imidazol-2-yl)ethyl)propanamido)methyl)-2-methoxybenzoate
Nomero ya Katalogi SZ-2078
CAS: 1137026-67-5
Isuku: 99%
Ikoreshwa rya Eluxadoline
Telefoni igendanwa/Wechat/WhatsApp: +86-13681683526
Imeri:lchen@syncozymes.com
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Eluxadoline Intermediate (S)-Methyl 2-Methoxy-5-((1-(4-phenyl-1H-imidazol-2-yl)ethylamino)methyl)benzoate
Nomero ya Katalogi SZ-2077
CAS: 1391712-57-4
Isuku: 99%
Ikoreshwa rya Eluxadoline
Telefoni igendanwa/Wechat/WhatsApp: +86-13681683526
Imeri:lchen@syncozymes.com
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Adapalene Intermediate 1-(5-bromo-2-methoxy-phenyl)adamantane
Nomero ya Katalogi SZ-1559
CAS: 104224-63-7
Isuku: 99%
Koresha Adpalene
Telefoni igendanwa/Wechat/WhatsApp: +86-13681683526
Imeri:lchen@syncozymes.com
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Eluxadoline Intermediate (S)-Methyl 2-Methoxy-5-((1-(4-phenyl-1H-imidazol-2-yl)ethylamino)methyl)benzoate aside oxalic
Nomero ya Katalogi SZ-2077
CAS: 2046303-09-5
Isuku: 99%
Ikoreshwa rya Eluxadoline
Telefoni igendanwa/Wechat/WhatsApp: +86-13681683526
Imeri:lchen@syncozymes.com
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Ibrutinib Intermediate (S)-1-Boc-3-hydroxypiperidine
Nomero ya Katalogi SZ-1527
CAS: 143900-44-1
Isuku: 99%
Ikoreshwa rya Ibrutinib
Telefoni igendanwa/Wechat/WhatsApp: +86-13681683526
Imeri:lchen@syncozymes.com
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![Ibrutinib Intermediate 3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine](https://cdn.globalso.com/syncozymesnad/3-4-phenoxyphenyl-1H-pyrazolo34-dpyrimidin-4-amine.jpg)
Ibrutinib Intermediate 3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Nomero ya Katalogi SZ-2028
CAS: 330786-24-8
Isuku: 99%
Ikoreshwa rya Ibrutinib
Telefoni igendanwa/Wechat/WhatsApp: +86-13681683526
Imeri:lchen@syncozymes.com
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Ibrutinib Intermediate 5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile
Nomero ya Katalogi SZ-2028-4
CAS: 330792-70-6
Isuku: 99%
Ikoreshwa rya 25kg/umufuka
Telefoni igendanwa/Wechat/WhatsApp: +86-13681683526
Imeri:lchen@syncozymes.com
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Phenylalanine dehydrogenase (PDH)
Ku bijyanye na Phenylalanine dehydrogenase
ES-PDH: Ubwoko bwa oxidoreductase. Igisubizo cyiza gishobora gukurura deamination ya oxidative y'umunyu wa L phenylalanine mu gihe hari NAD kugira ngo ikore umunyu wa phenylpyruvate, kandi igisubizo gisubira inyuma gishobora gukurura ikorwa ry'umunyu wa aside amine ujyanye n'uwo munyu wa phenylpyruvate. Syncozymes yakoze ibintu 8 bya phenylalanine dehydrogenase (ifite inomero ES-PDH-101~ES-PDH-108). ES-PDH ishobora gukoreshwa mu gutegura umunyu wa phenylalanine cyangwa umunyu wa aside amine ujyanye n'uwo munyu wa aside phenylpyruvic cyangwa ibikomoka kuri wo.
Ubwoko bw'ingaruka za "catalytic reaction":
Telefoni igendanwa/Wechat/WhatsApp: +86-13681683526
Imeri:lchen@syncozymes.com
