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Oxynitrilase (HNL)
Ibyerekeye oxynitrilase
ES-HNLs: Enzyme yo mu rwego rwa enantioselectively ituma hiyongeraho HCN kuri aldehydes (ketone) kugirango ibone alcool yo mu bwoko bwa R cyangwa S, ishobora guhinduka muburyo butandukanye bwibiyobyabwenge cyangwa abahuza ibiyobyabwenge hakoreshejwe uburyo bwa chimique.
Hariho ubwoko 29 bwibicuruzwa bya oxynitrilase (Umubare nka ES-HNL-101 ～ ES-HNL-129) byakozwe na SyncoZymes.SZ-HNL nigikoresho cyingirakamaro kuri regio- na stereo- guhitamo synthesis ya (R) -cyanohydrins cyangwa (S) -cyanohydrins biva muburyo butandukanye bwa aromatic, aliphatic na heterocyclic aldehydes cyangwa na ketone.
Ubwoko bwa catalitiki yerekana:
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E-Mail:lchen@syncozymes.com
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Nitro reductase (NTR)
Kubijyanye na nitro reductase
ES-NTRs: Ese flavoenzymes itera kugabanya NAD (P) H iterwa no kugabanuka kwamatsinda ya nitro kuri nitroaromatic na nitroheterocyclic ivanze na hydroxylamino na / cyangwa ibikomoka kuri amino.Zikoreshwa cyane muri synthesis organic ya hydroxylamine ya aromatic na amine aromatic, kuvura ibibyimba, gutahura ibinyabuzima no kwangiza ibidukikije.Hariho ubwoko 12 bwibicuruzwa bya Nitro (NTR) (Umubare nka ES-NTR-101 ~ ES-NTR-112) byakozwe na SyncoZymes.
Terefone / Wechat / WhatsApp: + 86-13681683526
E-Mail:lchen@syncozymes.com
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Aldolase (DERA)
ES-DERAs: Irashobora guhagarika neza stereoselective yongeyeho ketone yabaterankunga kuri reseptor aldehydes.Byongeye kandi, reaction irashobora gukorwa mugisubizo cyamazi ya pH idafite aho ibogamiye nta ngamba zidasanzwe zo gukingira.Biri mucyiciro cya I aldolase, ikora Shiff base mubikorwa bya catalitiki.Substrate ihujwe hamwe na amino itsinda ryurubuga rukora kugirango itangire gucika no gushinga ubumwe.Itandukaniro riri hagati ya DERAs nizindi aldolase nuko insimburangingo zitanga ari aldehydes kandi zishobora gukurikiranwa na aldehydes ikomeza.
Terefone / Wechat / WhatsApp: + 86-13681683526
E-Mail:lchen@syncozymes.com
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Cytochrome P450 monooxygenase (CYP)
Ibyerekeye CYP
ES-CYPs: Urwego rwimisemburo ya redox hamwe na mercaptan-heme nkikigo gikora kugirango uhindure ogisijeni.Ni okisijene ya terminal kandi ikenera heme kugirango ikore ogisijeni.
Cytochrome P450 monooxygenase itera okiside, epoxidation na hydroxylation ya alkyl, hydroxylation na okiside ya ammonia, okiside ya sulfure, dealkylation (ogisijeni, sulfure, amoniya), okiside dehydrogenation, deamination na dehalogenation.
Hariho ubwoko 8 bwibicuruzwa bya cytochrome P450 monooxygenase (Umubare nka ES-CYP-101 ～ ES-CYP-108) byakozwe na SyncoZymes.Terefone / Wechat / WhatsApp: + 86-13681683526
E-Mail:lchen@syncozymes.com
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Okiside ya alcool (AOX)
Ibyerekeye okiside ya alcool
ES-AOXs: Iyi misemburo irashobora guhagarika okiside ya alcool yuzuye amavuta cyangwa aryl-alcool kugirango ibe aldehydes.Bakoresha ogisijeni ya molekile ariko ntibisaba cofactor yongeyeho hanze, na hydrogen peroxide yakozwe.
Hariho ubwoko 6 bwibicuruzwa bya alcool (Umubare nka ES-AOX-101 ~ ES-AOX-106) byakozwe na SyncoZymes.ES-AOX101 na ES-AOX102 bahitamo ibinyobwa bisindisha bya alifatique, ES-AOX103 ~ ES-AOX105 bahitamo ibinyobwa bisindisha, naho ES-AOX106 ni okiside ya cholesterol.SZ-AOX nigikoresho cyingirakamaro muguhagarika okiside ya alcool yibinure cyangwa aryl-alcool kugirango itange aldehydes.
Ubwoko bwa catalitiki yerekana:
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E-Mail:lchen@syncozymes.com
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D-Amino aside dehydrogenase (D-AADH)
Ibyerekeye aside D-Amino dehydrogenase
ES-D-AADH (D-Amino aside dehydrogenase): enzyme ishobora kugabanya aside 2-keto muri aside D-amino ihuye.Igisubizo gikeneye NADP (H) hamwe n’umuterankunga wa ammonia (nka ammonia cyangwa ion amonium).Hariho ubwoko 17 bwa D-amino acide dehydrogenase (Umubare nka ES-DAADH-101 ~ ES-DAADH-117) wakozwe na SyncoZymes.
Ubwoko bwa catalitiki yerekana:
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E-Mail:lchen@syncozymes.com
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Esterase & Lipase (PLE & CALB)
Ibyerekeye Esterase & Lipase
ES-PLEs: Icyiciro cya hydrolase itera gushiraho no gusenyuka kwa ester.Barashobora kugira uruhare muburyo butandukanye bwibinyabuzima, nka esterification, transesterification na hydrolysis.Zikoreshwa cyane mubice byinshi nko gutunganya ibiribwa, inganda zikora imiti, biomedicine, imiti ya chiral no kuvura ibidukikije.
Terefone / Wechat / WhatsApp: + 86-13681683526
E-Mail:lchen@syncozymes.com
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Epoxide hydrolase (EH)
Ibyerekeye hydrolase ya epoxide
EH ni ether hydrolase itera hydrolysis ya stereoselective hydrolysis ya epoxide yubwoko kugirango itange epoxide 1, 2-diol kandi ikora neza, ishobora gukoreshwa mugukemura chiral ya epoxide cyangwa gutegura diyoloji ya chiral.Zikoreshwa cyane mubuvuzi no mubindi bice.Hariho ubwoko 3 bwibicuruzwa bya epoxide hydrolase (Umubare nka ES-EH-101 ～ ES-EH-103) byakozwe na SyncoZymes.ES-EH nigikoresho cyingirakamaro muguhindura synthesis ya chiral alcool binyuze muri hydrolysis ya stereoselective hydrolysis ya aliphatic na aromatic epoxide.
Ubwoko bwa catalitiki yerekana:
Terefone / Wechat / WhatsApp: + 86-13681683526
E-Mail:lchen@syncozymes.com
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Kora dehydrogenase (FDH)
Ibyerekeye Gukora dehydrogenase
ES-FDH.FDH ikoreshwa kenshi muguhindura coenzyme NADH.Hariho ubwoko 4 bwibicuruzwa bya enzyme ya FDH (ES-FDH-101 ~ ES-FDH-104) byakozwe na SyncoZymes, muri byo ES-FDH102 ifite ibikorwa byinshi kandi ni byo FDH isabwa cyane.
Ubwoko bwa catalitiki yerekana:
Terefone / Wechat / WhatsApp: + 86-13681683526
E-Mail:lchen@syncozymes.com
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Glucose dehydrogenase (GDH)
Ibyerekeye Glucose dehydrogenase
ES-GDH.GDH ikoreshwa kenshi muguhindura coenzyme NAD (P) H mumirima ya biocatalyse hamwe nindi misemburo nyamukuru.Hariho ubwoko 10 bwibicuruzwa bya enzyme ya GDH (ES-GDH-101 ~ ES-GDH-110) byakozwe na SyncoZymes, muri byo ES-GDH110 ifite ibikorwa byinshi kandi ni byo GDH isabwa cyane.
Ubwoko bwa catalitiki yerekana:
Terefone / Wechat / WhatsApp: + 86-13681683526
E-Mail:lchen@syncozymes.com
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Monoamine oxydease (MAO)
Ibyerekeye okiside ya Monoamine
ES-MAO (Monoamine oxydease): MAO itera okiside yangiza ya monoamine kugirango itange hydrogen peroxide, ammonia na aldehydes ihuye.Mubikorwa bya catalitiki, ogisijeni irakenewe nka okiside.Hariho ubwoko 6 bwibicuruzwa bya enzyme ya MAO (Umubare nka ES-MAO-101 ～ ES-MAO-106) byakozwe na SyncoZymes, bishobora gukoreshwa muguhagarika okiside ya monoamine.
Ubwoko bwa catalitiki yerekana:
Terefone / Wechat / WhatsApp: + 86-13681683526
E-Mail:lchen@syncozymes.com
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Lactate Dehydrogenase (LDH)
Ibyerekeye Lactate dehydrogenase
Hariho ubwoko 1 bwibicuruzwa bya LDH enzyme (Umubare nka ES-LDH) byakozwe na SyncoZymes.LDH irashobora gutuma igabanuka rya pyruvate kuri aside L-lactique, cyangwa kugabanya izindi aside zisa α-keto.Mubikorwa bya catalizike, NADH irakenewe nkabatwara hydrogen.
Ubwoko bwa reaction ya dehydrogenasecatalytic
Terefone / Wechat / WhatsApp: + 86-13681683526
E-Mail:lchen@syncozymes.com
