SyncoZymes

ibicuruzwa

Ene reductase (ERED)

Ibisobanuro bigufi:

Ibyerekeye ene reductase

ES-EREDs: Mumuryango wumusemburo ushaje wumuhondo ugabanya guhitamo C = C muri α, β -ibintu bituzuye hamwe nitsinda rikurura electron.Zikoreshwa cyane mubushakashatsi bwibikomoka kuri aside amine, ibintu bioaktike, abahuza imiti, ibirungo hamwe na chiral.

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E-Mail:lchen@syncozymes.com


Ibicuruzwa birambuye

Ibicuruzwa

Kubijyanye no kugabanya ene:

ES-EREDs itera ubwoko butandukanye bwububiko kubera ubunini bwagutse.Muri rusange, C = C ya α, β -ibintu byuzuye byuzuye hamwe na matsinda akurura electron (harimo ketone aldehyde, amatsinda ya nitro, acide karubike, esters, anhydride, lactone, imine, nibindi) bigabanuka byoroshye na ES-EREDs, ariko idakoreshwa inshuro ebyiri ntabwo.

Hariho ubwoko 46 bwibicuruzwa bya ERED enzyme (Umubare nka ES-ERED-101 ~ ES-ERED-146) byakozwe na SyncoZymes.

Uburyo bwa Catalitike:

Ene reductase ERED1

Amakuru y'ibicuruzwa:

Ene reductase ERED2
Enzymes Kode y'ibicuruzwa Ibisobanuro
Ifu ya Enzyme ES-ERED-101 ~ ES-ERED-146 urutonde rwa 46 Ene Kugabanya, 50 mg buri kintu 46 * 50mg / ikintu, cyangwa ubundi bwinshi
Igikoresho cyo kwerekana (SynKit) ES-ERED-4600 urutonde rwa 46 Ene Kugabanya, 50 mg buri kintu 46 * 50mg / ikintu, cyangwa ubundi bwinshi

Ibyiza:

Sub Substrate yihariye.
Guhitamo chiral ikomeye.
Guhindura byinshi.
Ibicuruzwa bike.
Conditions Imiterere yoroheje.
Yangiza ibidukikije.
Safety Umutekano muke.

Amabwiriza yo gukoresha:

➢ Mubisanzwe, sisitemu yogukora igomba kuba irimo substrate, igisubizo cya buffer (reaction reaction pH), coenzymes (NAD (H) cyangwa NADP (H)), sisitemu yo kuvugurura coenzyme (urugero glucose na glucose dehydrogenase) na ES-ERED.
ES ES-EREDs zose zirashobora kugeragezwa muburyo bwa reaction hejuru cyangwa hamwe na ERED Yerekana (SynKit ERED).
Types Ubwoko bwose bwa ES-EREDs bujyanye nuburyo bwiza bwo kwitwara bugomba kwigwa kugiti cye.
Kwibanda cyane Substrate cyangwa ibicuruzwa hamwe bishobora kubuza ibikorwa bya ES-ERED.Ariko, kubuzwa birashobora koroherezwa mugice cyo kongeramo substrate.

Ingero zo gusaba:

Urugero rwa 1 (α, β-aldehydes idahagije cyangwa ketone)(1):

Ene reductase ERED3

Urugero rwa 2 (α, β-acide karubasi ya acide n'ibiyikomokaho)(2):

Ene reductase ERED4

Ububiko:

Komeza imyaka 2 munsi -20 ℃.

Icyitonderwa:

Ntuzigere uhura nibihe bikabije nka: ubushyuhe bwo hejuru, hejuru / hasi ya pH hamwe nubushakashatsi bwimbitse.

Reba:

1. Lucídio C, Fardelone J, Augusto R, e tal.J.Mol.Catal.B: Enzym., 2004, 29: 41-45.
2. Stueckler C, Hall M, Ehammer H, e tal..Org.Lett, 2007, 9 (26): 5409-5411.


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