Ketoreductase (KRED)
KRED ikomoka kuri SyncoZymes: Hari ubwoko 191 bw'ibicuruzwa bya enzyme bya KRED (Umubare nka ES-KRED-101~ES-KRED-291) byakozwe na SyncoZymes. SZ-KRED ishobora gukoreshwa cyane mu kugabanya aldehydes, beta-ketone esters, α-ketone esters na ketones mu turere no mu buryo bwa stereoselective.
Ubwoko bw'ingaruka za "catalytic reaction":
| Imisemburo | Kode y'igicuruzwa | Ibisobanuro |
| Ifu ya enzyme | Ifu ya enzyme | seti ya Ketoreductases 187, 50 mg buri kimwe 187 ibintu * 50mg / ikintu, cyangwa ikindi gipimo |
| Agakoresho ko gusuzuma (SynKit) | ES-KRED-18100 | seti ya Ketoreductases 181, 1 mg buri kimwe 181 ibintu * 1mg / ikintu |
★ Uburyo bwinshi bwo gukoresha substrate.
★ Guhitamo gukomeye kw'abacuranzi.
★ Uburyo bwo guhindura ibintu bukoresha ubushobozi bwo hejuru.
★ Ibicuruzwa bike biva kuri ibyo.
★ Indwara zoroheje zo mu mutwe.
★ Irinda ibidukikije.
➢ Hakwiye gukorwa isuzuma rya enzyme ku bice bimwe na bimwe by’ingenzi bitewe n’imiterere yabyo, kandi hagakorwa enzyme ihindura imiterere yabyo ku bice bimwe na bimwe by’ingenzi.
➢ Ntukigere uhura n'ibintu bikomeye nko: ubushyuhe bwinshi, pH iri hejuru/hasi n'umusemburo w'ibinyabuzima ufite ubushyuhe bwinshi.
➢ Ubusanzwe, sisitemu y'ibisubizo igomba kuba irimo substrate, umuti wa buffer, coenzymes (NAD (H) cyangwa NADP (H)), sisitemu yo kuvugurura coenzymes (urugero: glucose na glucose dehydrogenase).
➢ KRED igomba kongerwaho nyuma muri sisitemu y'ibisubizo, nyuma yuko pH n'ubushyuhe bihinduwe hakurikijwe imiterere y'ibisubizo.
➢ Ubwoko bwose bwa KRED bufite uburyo butandukanye bwo gusubiza ibintu neza, bityo buri kimwe muri byo kigomba kwigwaho ku giti cyacyo.
Urugero rwa 1(1):
Urugero rwa 2(2):
1. Li Z, Liu WD, Chen X, e tal. Tetrahedron, 2013, 69, 3561-3564.
2. Ni Y, Li CX, Ma HM, e tal. Koresha Microbiol Biotechnol, 2011, 89: 1111-1118.
