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Nucloside fosifora (NP)
Ibyerekeye nucleoside fosifora
Hariho ubwoko 3 bwibicuruzwa bya NP enzyme (Umubare nka ES-NP-101 ~ ES-NP-103) byakozwe na SyncoZymes.ES-NP-101 ni purine nucleoside fosifora, ES-NP-102 na ES-NP-103 ni pyrimidine nucleoside fosifori.Nucleosidephosphorylase irashobora kubora nucleoside mubice na fosifate ya pentose.Nucleoside phosphorylase irashobora kugabanywamo purine nucleoside fosifora na pyrimidine nucleoside phosphorylase ukurikije ibyifuzo bya nucleoside.Posine nucleoside fosifora irashobora guhinduranya adenosine kuri adenine, inosine kuri hypoxanthine, guanosine kuri guanine, kandi ikabyara fosifate ya ribose icyarimwe.Pyrimidine nucleoside fosifora irashobora guhinduranya uridine kuri uracil kandi ikabyara fosifate ya ribose.
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Hydroaminase (HAM)
Ibyerekeye Hydroaminase
Hariho ubwoko 2 bwibicuruzwa bya HAM enzyme (Umubare nka ES-HAM-101 ~ ES-HAM-102) byakozwe na SyncoZymes.HAM irashobora guhagarika ammoniation ya acide enoic cyangwa ibiyikomokaho kugirango ikore aside chiral amino.HAM irashobora gukoreshwa mugushushanya chiral amino acide (cyangwa chiral amine) ivuye muri acide enoic (cyangwa alkenes).Umuterankunga wa Amoniya, nk'amazi ya amoniya cyangwa umunyu wa amonium, birakenewe.
Ubwoko bwa Hydroaminase catalitike yubwoko
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CALB yimuwe
CALB
Recombinant Lipase B yo muri Candida antarctica (CALB) ikorwa na fermentation yarohamye hamwe na pasitori ya Pichia yahinduwe.
CALB irashobora gukoreshwa mugice cyamazi cyangwa icyiciro cya catalitiki esterifike, esterolysis, transesterifike, impeta ifungura polyester synthesis, aminolysis, hydrolysis ya amide, acylation ya amine hamwe ninyongera.
CALB hamwe no guhitamo chiral nyinshi no guhitamo imyanya, bityo irashobora gukoreshwa cyane mugutunganya amavuta, ibiryo, ubuvuzi, kwisiga nizindi nganda zikora imiti.
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NADH oxydease (NOX)
Ibyerekeye okiside ya NADH
ES-NOX (NADH oxydease): NOX itera okiside ya NADH kuri NAD +, kandi ni iya oxydeore.Muburyo bwa okiside, O2 irakenewe nka okiside, kandi igabanuka kuri H2O cyangwa H2O2.Hariho ubwoko 4 bwibicuruzwa bya enzyme ya NOX (ES-NOX-101 ~ ES-NOX-104) byakozwe nisosiyete yacu, bishobora gukoreshwa muguhindura okiside ya coenzyme NAD +.
Ubwoko bwa catalitiki yerekana:
or
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Phenylalanine ammonia lyase (PAL)
Ibyerekeye Phenylalanine ammonia lyase
ES-PAL: Icyiciro cyimisemburo itera kwanduza L-phenylalanine itaziguye kuri acide transinnamic.Syncozymes yateje imbere ibintu 10 bya fenylalanine ammonia lyase (inomero ya ES-PAL-101 ~ ES-PAL-110), ishobora gukoreshwa mugusenya cyangwa gusubiza inyuma fenilalanine n'ibiyikomokaho.
Ubwoko bwa catalitiki yerekana:
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Catalase (CAT)
Ibyerekeye Catalase
ES-CAT (Catalase): itera kubora kwa H2O2 muri ogisijeni n'amazi.Bibaho cyane cyane muri mitochondriya, reticulum ya endoplasmeque, umwijima winyamanswa hamwe ningirangingo zamaraso zitukura, cyane cyane mwumwijima mwinshi cyane, bitanga umubiri wo kwirinda antioxydeant kumubiri.Muri biocatalyse, ikoreshwa cyane cyane mugukuraho reaction ya hydrogène peroxide yibicuruzwa no kugabanya kubuza no kudakora enzyme na hydrogen peroxide.Hariho ubwoko 1 gusa bwibicuruzwa bya CAT enzyme byakozwe na SyncoZymes (Umubare nka ES-CAT).
Ubwoko bwa catalitiki yerekana:
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Lysine oxydease (LO)
Ibyerekeye okiside ya Lysine
ES-LO (Lysine oxydease): itera okiside ya L-lysine kugeza kuri 6-amino-2-oxohexanoic aside (cyangwa lactone yayo).Hariho ubwoko 1 gusa bwibicuruzwa bya LO enzyme (Umubare nka ES-LO) byakozwe na SyncoZymes.
Ubwoko bwa catalitiki yerekana:
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Foshokinase (PKase)
Ibyerekeye Phosphokinase
ES-PKase (Phosphokinase): itera ihererekanyabubasha ryamatsinda ya fosifate kuri ATP mubindi bikoresho.Ihindura kandi ihererekanyabubasha ryamatsinda ya fosifate kurindi nucleoside ya triphosifate rimwe na rimwe.Kinase nyinshi ikenera ibyuma bya ion kugirango bigire uruhare mubitekerezo (muri rusange Mg2 +).Hariho ubwoko 21 bwibicuruzwa bya enzyme ya PKase (Umubare nka ES-PKase101 ~ ES-PKase-121) byakozwe na SyncoZymes.
Ubwoko bwa catalitiki yerekana:
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Cyclooxygenase (COX)
Ibyerekeye Cyclooxygenase
ES-COX (Cyclooxygenase): itera ihinduka ryimigozi ya C = C kuri epoxide.Hariho ubwoko 11 bwibicuruzwa bya enzyme ya COX (Umubare nka ES-COX101 ~ ES-COX-111) byakozwe na SyncoZymes.Ukurikije uburyo butandukanye bwa catalitiki, COX ya SyncoZymes igabanijwemo haloperoxidase na styrene monooxygenase.ES-COX101, 102, 107-111 ni iya haloperoxidase, naho ES-COX103-106 ni iya monoxygenase ya styrene.
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Cyclohexanone monooxygenase (CHMO)
Ibyerekeye Cyclohexanone monooxygenase
ES-CHMO (Cyclohexanone monooxygenase): Baeyer Villiger monooxygenase (BVMO) hamwe na cyclohexanone nka substrate, irashobora okiside cyclohexanone kuri cyclohexanol ikoresheje ogisijeni.
Nubwoko bwa flavin enzyme.Okiside ya flavin yagabanutse kuri flavin binyuze mukuzenguruka kugabanya coenzyme II (NADPH) kugirango okiside itaha.Kubwibyo, cofactor NADPH irakenewe mugihe cya flavin.Hariho ubwoko 1 gusa bwibicuruzwa bya enzyme ya CHMO (Umubare nka ES-CHMO101) byakozwe na SyncoZymes, bishobora gukoreshwa muguhindura cyclohexanone kuri cyclohexanone.
Ubwoko bwa catalitiki yerekana:
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Carboxylic aside reductase (CAR)
Ibyerekeye kugabanya aside ya Carboxylic
ES-CAR (Carboxylic aside reductase): itera kugabanuka kwitsinda rya carboxyl mumatsinda ya aldehyde.Mubikorwa bya catalitiki, gukora ATP na coenzyme NADPH birasabwa nkabatwara hydrogen.Hariho ubwoko 2 bwibicuruzwa bya CAR enzyme (Umubare nka ES-CAR101 ~ ES-CAR-102) byakozwe na SyncoZymes.
Ubwoko bwa catalitiki yerekana:
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Transaldolase (TAL)
Ibyerekeye Transaldolase
ES-TAL (Transaldolase): ahanini yerekeza kuri transaldolase ya threonine, ishobora guhagarika reaction yo guhuza ibikomoka kuri hyd-hydroxyphenylalanine ikomoka kuri threonine na benzaldehyde.TAL ni enzyme ya PLP.Hariho ubwoko 1 gusa bwibicuruzwa bya TAL enzyme (Umubare nka ES-TAL101) byakozwe na SyncoZymes, bishobora gukoreshwa muguhuza β-hydroxyphenylalanine nibiyikomokaho.
Ubwoko bwa catalitiki yerekana:
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E-Mail:lchen@syncozymes.com
