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Fosforasi ya Nucloside (NP)
Ku bijyanye na fosifori ya nucleoside
Hari ubwoko butatu bw'ibikomoka kuri enzyme ya NP (Umubare nka ES-NP-101 ~ ES-NP-103) byakozwe na SyncoZymes. ES-NP-101 ni purine nucleoside phosphorylase, ES-NP-102 na ES-NP-103 ni pyrimidine nucleoside phosphorylase. Nucleosidephosphorylase ishobora gutandukanya nucleosides mo bases na pentose phosphate. Nucleoside phosphorylase ishobora kugabanywamo purine nucleoside phosphorylase na pyrimidine nucleoside phosphorylase hakurikijwe ibyo bases za nucleoside zikunda. Purine nucleoside phosphorylase ishobora gusya adenosine kuri adenine, inosine kuri hypoxanthine, guanosine kuri guanine, no gukora ribose phosphate icyarimwe. Pyrimidine nucleoside phosphorylase ishobora gusya uridine kuri uracil no gukora ribose phosphate.
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Hydroaminase (HAM)
Ku bijyanye na Hydroaminase
Hari ubwoko bubiri bw'umusaruro wa enzyme ya HAM (Umubare nka ES-HAM-101~ ES-HAM-102) wakozwe na SyncoZymes. HAM ishobora gukurura aside enoic cyangwa ibiyikomokaho kugira ngo ikore aside chiral amine. HAM ishobora gukoreshwa mu gukora aside chiral amine (cyangwa amine chiral) iva muri aside enoic (cyangwa alkenes). Umuntu utanga amino, nk'amazi ya amonia cyangwa umunyu wa amoniya, ni ngombwa.
Ubwoko bw'ingaruka za Hydroaminase catalytic
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CALB idakora neza
CALB
Lipase B ikomoka kuri Candida antarctica (CALB) ikorwa binyuze mu gushyushya amazi hifashishijwe Pichia pastoras yahinduwe mu buryo bwa genetike.
CALB ishobora gukoreshwa mu gice cy’amazi cyangwa igice cy’ibinyabuzima, esterolysis, transesterification, synthesis ya polyester ifunguye impeta, aminolysis, hydrolysis ya amides, acylation ya amines na addition reaction.
CALB ifite uburyo bwo guhitamo neza ibishushanyo mbonera bya chiral n'uburyo bwo guhitamo imyanya, bityo ikaba ishobora gukoreshwa cyane mu nganda zitunganya amavuta, ibiribwa, ubuvuzi, ubwiza n'izindi nganda zikora imiti.
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Imeri:lchen@syncozymes.com
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NADH oxidase (NOX)
Ku bijyanye na oksidase ya NADH
ES-NOX (NADH oxidase): NOX itera ogisijeni ya NADH muri NAD+, kandi ikaba iya ogisijeni. Mu gihe cyo ogisijeni, O2 irakenewe nk'iy'isukari, ikagabanuka ikaba H2O cyangwa H2O2. Hari ubwoko bune bw'ibicuruzwa bya enzyme ya NOX (ES-NOX-101~ES-NOX-104) byakozwe n'ikigo cyacu, bishobora gukoreshwa mu kongera ogisijeni ya coenzyme NAD+.
Ubwoko bw'ingaruka za "catalytic reaction":
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Imeri:lchen@syncozymes.com
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Phenylalanine ammonia lyase (PAL)
Ku bijyanye na Phenylalanine ammonia lyase
ES-PAL: Ubwoko bwa enzymes zituma L-phenylalanine ihinduka aside transcinnamic. Syncozymes yakoze ibintu 10 bya phenylalanine ammonia lyase (ifite inomero ES-PAL-101~ES-PAL-110), ishobora gukoreshwa mu gukuraho aside cyangwa gusubiza inyuma fenilalanine n'ibiyikomokaho.
Ubwoko bw'ingaruka za "catalytic reaction":
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Katalase (CAT)
Ku bijyanye na Catalase
ES-CAT (Catalase): ihindura uburyo H2O2 ibora mu mwuka wa ogisijeni n'amazi. Iboneka cyane cyane muri mitochondria, endoplasmic reticulum, umwijima w'inyamaswa n'uturemangingo dutukura tw'amaraso, cyane cyane mu mwijima uri ku rugero rwo hejuru, igatanga imikorere yo kurinda umubiri ku buryo bwo kurwanya antioxidant. Muri biocatalysis, ikoreshwa cyane cyane mu gukuraho peroxide ya hydrogen ikomoka ku bisubizo no kugabanya gukumira no guhagarika enzyme na peroxide ya hydrogen. Hari ubwoko bumwe gusa bw'ibicuruzwa bya enzyme ya CAT byakozwe na SyncoZymes (Numero nka ES-CAT).
Ubwoko bw'ingaruka za "catalytic reaction":
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Imeri:lchen@syncozymes.com
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Lysine oxidase (LO)
Ku bijyanye na Lysine oxidase
ES-LO (Lysine oxidase): itera ogisijeni ya L-lysine muri aside 6-amino-2-oxohexanoic (cyangwa lactone yayo). Hari ubwoko bumwe gusa bwa enzyme ya LO (Numero nka ES-LO) yakozwe na SyncoZymes.
Ubwoko bw'ingaruka za "catalytic reaction":
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Imeri:lchen@syncozymes.com
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Phosphokinase (PKase)
Ku bijyanye na Phosphokinase
ES-PKase (Phosphokinase): itera imbaraga mu kohereza amatsinda ya fosfeti kuri ATP mu bindi bintu. Itera imbaraga kandi mu kohereza amatsinda ya fosfeti ku zindi nucleoside za triphosphate rimwe na rimwe. Inyinshi muri kinase zikenera iyoni z'icyuma zivanze kugira ngo zigire uruhare mu gikorwa (muri rusange Mg2+). Hari ubwoko 21 bw'ibicuruzwa bya enzyme ya PKase (Umubare nka ES-PKase101~ ES-PKase-121) byakozwe na SyncoZymes.
Ubwoko bw'ingaruka za "catalytic reaction":
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Cyclooxygenase (COX)
Ku bijyanye na Cyclooxygenase
ES-COX (Cyclooxygenase): ihindura imiyoboro ya C=C muri epoxide. Hari ubwoko 11 bw'ibicuruzwa bya enzyme ya COX (Umubare nka ES-COX101~ ES-COX-111) byakozwe na SyncoZymes. Dukurikije uburyo butandukanye bwo gukaranga, COX ya SyncoZymes igabanyijemo haloperoxidase na styrene monooxygenase. ES-COX101, 102, 107-111 igize haloperoxidase, mu gihe ES-COX103-106 igize styrene monooxygenase.
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Imeri:lchen@syncozymes.com
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Cyclohexanone monooxygenase (CHMO)
Ku bijyanye na Cyclohexanone monooxygenase
ES-CHMO (Cyclohexanone monooxygenase): Baeyer Villiger monooxygenase (BVMO) hamwe na cyclohexanone nk'umusemburo, ishobora kohereza cyclohexanone muri cyclohexanol ikoresheje ogisijeni.
Ni ubwoko bwa enzyme ishingiye kuri flavin. Flavin ya oxidized igabanuka ikaba flavin mu gihe cyo kugabanya coenzyme II (NADPH) kugira ngo habeho oxidation itaha. Kubwibyo, cofactor NADPH ni ngombwa mu gihe cya flavin. Hari ubwoko bumwe gusa bwa enzyme ya CHMO (Umubare nka ES-CHMO101) yakozwe na SyncoZymes, ishobora gukoreshwa mu gukurura cyclohexanone muri cyclohexanone.
Ubwoko bw'ingaruka za "catalytic reaction":
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Kugabanya aside karubokisilike (CAR)
Ku bijyanye no kugabanya aside karubokisilike
ES-CAR (aside carboxylic reductase): itera imbaraga kugabanya itsinda rya carboxyl rijya muri aldehyde. Mu nzira ya catalytic, ATP activation na coenzyme NADPH ni byo bikenewe nk'ibitwara hydrogen. Hari ubwoko bubiri bw'ibicuruzwa bya enzymes za CAR (Umubare nka ES-CAR101~ ES-CAR-102) byakozwe na SyncoZymes.
Ubwoko bw'ingaruka za "catalytic reaction":
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Imeri:lchen@syncozymes.com
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Phenylalanine dehydrogenase (PDH)
Ku bijyanye na Phenylalanine dehydrogenase
ES-PDH: Ubwoko bwa oxidoreductase. Igisubizo cyiza gishobora gukurura deamination ya oxidative y'umunyu wa L phenylalanine mu gihe hari NAD kugira ngo ikore umunyu wa phenylpyruvate, kandi igisubizo gisubira inyuma gishobora gukurura ikorwa ry'umunyu wa aside amine ujyanye n'uwo munyu wa phenylpyruvate. Syncozymes yakoze ibintu 8 bya phenylalanine dehydrogenase (ifite inomero ES-PDH-101~ES-PDH-108). ES-PDH ishobora gukoreshwa mu gutegura umunyu wa phenylalanine cyangwa umunyu wa aside amine ujyanye n'uwo munyu wa aside phenylpyruvic cyangwa ibikomoka kuri wo.
Ubwoko bw'ingaruka za "catalytic reaction":
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