Amine Dehydrogenase (AmDH)
Ibisobanuro bigufi:
Ku bijyanye na Amine Dehydrogenase
ES-AmDH (Amine Dehydrogenase): enzyme ishobora gukurura amoniyasiyo y'itsinda rya karuboni ikayigabanya ikaba itsinda rya amino. Ni enzyme ishingiye kuri coenzyme NADH, kandi NADH ikora nk'umuyoboro wa hydrogen. Hari ubwoko bune bw'ibicuruzwa bya enzyme ya AmDH (Umubare nka ES-AmDH101 ~ ES-AmDH104) byakozwe na SyncoZymes, ishobora gukoreshwa mu gukusanya aldehydes na ketones mu buryo bwa regioselective cyangwa stereoselective reductive.
Ubwoko bw'ingaruka za "catalytic reaction":
Telefoni igendanwa/Wechat/WhatsApp: +86-13681683526
Imeri:lchen@syncozymes.com
★ Uburyo bwinshi bwo gukoresha substrate.
★ Guhitamo gukomeye kw'abacuranzi.
★ Guhinduranya ibintu byinshi.
★ Ibicuruzwa bike biva kuri ibyo.
★ Indwara zoroheje zo mu mutwe.
★ Irinda ibidukikije.
➢ Ubusanzwe, uburyo bwo gusubiza ibintu bugomba kuba burimo substrate, buffer solution, enzyme, coenzyme na coenzyme regeneration system (urugero: glucose na glucose dehydrogenase).
➢ AmDH igomba kongerwaho nyuma mu buryo bw'imikorere, nyuma y'uko pH n'ubushyuhe bihinduwe hakurikijwe imiterere y'imikorere.
Urugero rwa 1 (Gukora amine za chiral zijyanye nazo binyuze mu gutuma alkyl aryl ketones zigabanuka)(1):
Bika ahantu hatagera ku gipimo cya -20°C imyaka 2.
Ntukigere uhura n'ibintu bikomeye nko: ubushyuhe bwinshi, pH iri hejuru/hasi ndetse n'ibinyabutabire byinshi.
1. Kong W, Liu Y, Huang C, n'abandi. Angewandte Chemie Edition International Edition, 2022: e202202264.
