β-Nicotinamide Mononucleotide (NMN)
Vuba aha, hari inkuru nziza mubijyanye na NMN - nyuma yo gusuzumwa byimazeyo na komite yabigize umwuga y’ikigo cy’Amerika gishinzwe ibiryo n’ibiyobyabwenge (FDA), ibikoresho fatizo bya NMN bya Shangke Biopharmaceutical (Shanghai) Co., Ltd. (bikurikira) kuri "Shangke Bio") byemejwe n’Amerika muri Amerika FDA NDI yemeza ko ibikoresho byayo bya NMN bishobora gukoreshwa ku mugaragaro mu gukora, kugurisha no guteza imbere inyongeramusaruro muri Amerika, kandi ushobora kubisanga ku muyobozi wa FDA. urubuga nkimirire mishya yuzuza ibikoresho bibisi, nimero 1247.
FDA NDI nuburyo bukomeye bwo gutanga ibyemezo ku isoko ry’Amerika.Kubona iki cyemezo ntabwo bivuze gusa ko umutekano nubuziranenge bwibicuruzwa bya Shangke Bio aribyobizwi cyane, ariko kandi bifasha iterambere rihoraho ryiterambere ryinganda za NMN mugihe kirekire.
| Izina ryimiti | Nicotinamide Mononucleotide |
| Synonyme | NICOTINAMIDE-1-IUM-1-BETA-D-RIBOFURANOSIDE 5'-FOSPHATE |
| Umubare CAS | 1094-61-7 |
| Uburemere bwa molekile | 334.22 |
| Inzira ya molekulari | C11H15N2O8P |
| EINECS 号: | 214-136-5 |
| Ingingo yo gushonga | 166 ° C (Ukuboza) |
| ububiko bwa temp. | -20 ° C. |
| gukemura | DMSO (Buhoro, Bishyushye), Methanol (Buhoro), Amazi (Buhoro) |
| ifishi | Birakomeye |
| ibara | Umweru kugeza Umuhondo |
| Merk | 13,6697 |
| BRN | 3570187 |
| Igihagararo: | Hygroscopique |
| InChIKey | DAYLJWODMCOQEW-TURQNECASA-N |
| Ikizamini | Ibisobanuro |
| Kugaragara | Ifu yera-yera-ifu ya kristaline |
| Ibirimo sodium | ≤1% |
| agaciro ka pH (100mg / ml) | 2.0 ~ 4.0 |
| Isuku | ≥99.0% |
| Ibirimo amazi | ≤1% |
| Ibyuma biremereye | <10ppm |
| Arsenic | <0.5ppm |
| Kuyobora | <0.5ppm |
| Mercure | <0.1ppm |
| Cadmium | <0.5ppm |
| Ibisigisigi | Ethanol≤1000ppm |
| Umubare wa Aerobic Microbial Kubara | <750cfu / g |
| Umusemburo & Mold | <25cfu / g |
| Igiteranyo cyuzuye | ≤0.92MPN / g |
| E. Coli | Ibibi |
| Salmonella | Ibibi |
| Staph.Aureus | Ibibi |
| Suzuma (ku buryo budasanzwe) | ≥99.0% |
| Igipimo cyo gukuramo | ≥95% |
| Ubucucike bwinshi | Raporo yamakuru |
Ipaki:Icupa, umufuka wa aluminium, 25kg / Ikarito yingoma, cyangwa ukurikije ibyo umukiriya asabwa.
Imiterere y'Ububiko:Bika mu bikoresho byoroshye, birinda urumuri, kubikwa igihe kirekire ubike kuri 2 ~ 8 ° C cyangwa munsi.
Nikotinamide Mononucleotide (NMN) nuburyo bushya bwa vitamine B3 nintambwe 1 ibanziriza NAD + (Nicotinamide Adenine Dinucleotide).NMN niyambere ya selile NAD + igarura byagaragaye ko ifite akamaro ko kugarura selile muri vivo.
Nikotinamide Adenine Dinucleotide (NAD) ni imwe muri molekile zingenzi kandi zishimishije mumubiri.Irakenewe kubitekerezo birenga 500 byimikorere kandi bigira uruhare runini mugutunganya hafi y'ibinyabuzima byose byingenzi (Ansari na Raghava, 2010).Ikirenze byose, irashobora kutwemerera kubaho ubuzima bwiza kandi burambye.
Nikotinamide Adenine Dinucleotide (NAD) ibaho muburyo bwayo bwa okiside (NAD +) cyangwa yagabanutse (NADH), ibyo bikaba ari cofactors zingirakamaro za oxydeductase.
SyncoZyems nkuwambere kubona FDA NDI NMN yemewe ninganda zitanga ibikoresho fatizo, uhagarariye umuyobozi wa FDA wemera NMN nkibintu bishya bishobora gutangira kwemerwa no kwemezwa kubintu byongera ibiryo muri Amerika.
