β-Nicotinamide adenine dinucleotide fosifate hydrat (NADP)
SyncoZymes (Shanghai) Co, Ltd. niyambere ikora kandi itanga β-Nicotinamide adenine dinucleotide fosifate hydrat (CAS: 53-59-8) ifite ubuziranenge.Turashobora gutanga COA, gutanga kwisi yose, bike kandi byinshi birahari.Niba ushimishijwe niki gicuruzwa, nyamuneka ohereza amakuru arambuye arimo numero CAS, izina ryibicuruzwa, ingano kuri twe.Nyamuneka hamagara:lchen@syncozymes.com
| Izina ryimiti | β-Nicotinamide adenine dinucleotide fosifate hydrat |
| Synonyme | β-Nicotinamide adenine dinucleotide fosifate hydrat |
| Umubare CAS | 53-59-8 |
| Uburemere bwa molekile | 743.41 |
| Inzira ya molekulari | C21H28N7O17P3 |
| EINECS No. | 200-178-1 |
| ububiko bwa temp. | Gumana ahantu hijimye, Inert ikirere, Ubike muri firigo, munsi ya -20 ° C. |
| gukemura | H2O: 50 mg / mL, bisobanutse, umuhondo muto |
| pka | pKa1 3.9;pKa2 6.1 (kuri 25 ℃) |
| xmax | 260nm (lit.) |
| Merk | 14,6348 |
| Sisitemu yo Kwiyandikisha Ibintu | Adenosine 5 '- (trihydrogen diphosphate), 2' - (fosifate ya dihydrogen), P'.fwdarw.5'-ester hamwe na 3- (aminocarbonyl) -1-.beta.-D-ribofuranosylpyridinium, umunyu w'imbere (53-59- 8) |
| Ikizamini | Ibisobanuro |
| Kugaragara | Ifu yera kugeza kumuhondo |
| Gukemura | 200mg / ml mu mazi |
| agaciro ka pH (100mg / ml) | 5.0 ～ 7.0 |
| Isesengura rya UV εat 260 nm na pH 7.5 | (18 ± 1.0) × 10³L / mol / cm |
| Ibirimo (kubisesengura byimikorere hamwe na G.6PDH kuri pH 7.5, ukoresheje spekitifotometero, abs.340nm, kuri anhydrous) | ≥90.0% |
| Isuku (na HPLC, agace ka%) | ≥95.0% |
| Ibirimo amazi (by KF) | ≤5% |
Ipaki:Icupa, umufuka wa aluminium, 25kg / Ikarito yingoma, cyangwa ukurikije ibyo umukiriya asabwa.
Imiterere y'Ububiko:Komeza uhagarare neza mwijimye, kubikwa igihe kirekire komeza kuri 2 ~ 8 ℃.
NADP ni coenzyme, ni ikintu kirimo nikotinamide adenine dinucleotide na molekile ya fosifate ihujwe na ester, kandi ibaho henshi.mw'isi y'ibinyabuzima.Imiterere yimiti, uburyo bwo kwinjiza ibintu, imiterere ya redox, nibindi bisa na NAD (Coenzyme I).NADP irashobora gukoreshwa cyane mubitekerezoitangizwa ninzoga zitandukanye za dehydrogenase, ketoreductase nizindi oxydeore.Nka: irashobora kugabanuka kuri NADPH na dehydrogenase nyinshi nkiyinka 6-fosifoglucose dehydrogenase (EC.1.1.1.49), 6-fosifogluconate dehydrogenase (EC.1.1.1.44).Ariko, ntabwo byanze bikunze ishobora kubyitwaramo na benshidehydrogenase ikoresha NAD, ntanubwo ishobora guhumeka neza nuyoboro wubuhumekero.Bitandukanye na NAD, ibaho cyane cyane muburyo bugabanutse mu ngirabuzimafatizo y'ibinyabuzima byo mu kirere.
Ukurikije ibicuruzwa, birashobora kugabanywa mubyiciro bikurikira: icyiciro cya biotransformation, igipimo cyo gusuzuma reagent, icyiciro cyibiryo byubuzima.
Urwego rwa Biotransformation: Irashobora gukoreshwa muguhuza imiti ihuza imiti na APIs, cyane cyane hamwe na enzymes ya catalitiki, nka ketoreductase (KRED),P450 monooxygenase (CYP), ikora dehydrogenase (FDH), glucose dehydrogenase (GDH), nibindi Tegereza.
Icyiciro cya Diagnostic reagent: Hamwe na enzymes zitandukanye zo gusuzuma, nkibikoresho fatizo byibikoresho byo gusuzuma.
Icyiciro cyibiryo byubuzima: Gushyira mu bikorwa ibiryo bya NADP biri mubushakashatsi niterambere.
