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SyncoZymes

ibicuruzwa

Ishusho ya Imine reductase (IRED)
  • Imiterere ya Imine (IRED)

Imiterere ya Imine (IRED)

Ibisobanuro bigufi:

Ku bijyanye na Imine reductase

ES-IRED: Ubwoko bwa enzymes zituma C=N igabanya umugozi wa CN. Ni iya enzyme ya redox, hamwe na coenzyme NADPH yo gutwara hydrogen. Dukurikije uburyo chiral ikunda ibicuruzwa, zishobora kugabanywamo R-IRED na S-IRED. Syncozymes yashyizeho imiyoboro 15 ya imine reductases (numbIRED ES-IRED-101-ES-IRED-115), ishobora gukoreshwa cyane mu kugabanya imiyoboro ya imine na stereoselective kugira ngo itegure imiyoboro ya mine.
Ubwoko bw'ingaruka za "catalytic reaction":

Imine reductase (IRED)2

Telefoni igendanwa/Wechat/WhatsApp: +86-13681683526

Imeri:lchen@syncozymes.com


Ibisobanuro birambuye ku gicuruzwa

Ibirango by'ibicuruzwa

Amakuru ku bicuruzwa:

Imiterere ya Imine (IRED)
Imisemburo Kode y'igicuruzwa Ibisobanuro
Ifu ya enzyme ES-IRED-101~ ES-IRED-114 seti ya 14 Imine Reductase, 50 mg buri imwe
Agakoresho ko gusuzuma enzyme y'amazi ya 96 ES-IRED-1400 seti ya 14 Imine Reductase, 1 mg buri imwe

Ibyiza:

★ Uburyo bwinshi bwo gukoresha substrate.
★ Guhitamo gukomeye kw'abacuranzi.
★ Guhinduranya ibintu byinshi.
★ Ibicuruzwa bike biva kuri ibyo.
★ Indwara zoroheje zo mu mutwe.
★ Irinda ibidukikije.

Amabwiriza yo gukoresha:

➢ Ubusanzwe, sisitemu yo gusubiza ibintu igomba kuba irimo substrate, solution ya buffer, enzyme, coenzyme, na sisitemu yo kuvugurura coenzyme.
➢ Ubwoko bwose bwa ES-IREDs bujyanye n'imiterere itandukanye myiza y'ibizamini bugomba kwigwa ukwabwo.
➢ Ubunini bwinshi bw'ibinyabutabire cyangwa ibikomoka ku bimera bishobora kubangamira imikorere ya ES-IRED. Ariko, ubu buryo bwo kubuza ibintu bushobora kugabanuka no kongeramo ibinyabutabire.

Ingero z'Ishyirwa mu Bikorwa:

Urugero rwa 1 (Biosynthesis ya chiral 2-methyl pyrrolidine)(1):

Imiterere ya Imine (IRED)3

Urugero rwa 2 (Biosynthesis ya amine ya kabiri)(2):

Imine reductase (IRED)4

Urugero rwa 3 (Kugabanya ibinyabutabire bya Cyclic)(3):

Imine reductase (IRED)5

Ububiko:

Bika ahantu hatagera ku gipimo cya -20°C imyaka 2.

Icyitonderwa:

Ntukigere uhura n'ibintu bikomeye nko: ubushyuhe bwinshi, pH iri hejuru/hasi ndetse n'ibinyabutabire byinshi.

Amareferensi:

1. Scheller PN, Fademrecht S, Hofelzer S, nabandi. ChemBioChem, 2014, 15, 2201-2204.
2. Wetzl D, Gand M, Ross A, n'abandi. ChemCatChem, 2016, 8, 2023-2026.
3. Li H, Luan ZJ, Zheng GW, n'abandi. Umujyanama. Synth. Catal. 2015, 357, 1692-1696.

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