β-Nicotinamide Mononucleotide (NMN)
Vuba aha, hari inkuru nziza mu bijyanye na NMN - nyuma y’isuzuma rikomeye ryakozwe n’akanama k’abahanga k’ikigo gishinzwe ibiribwa n’imiti muri Amerika (FDA), ibikoresho fatizo bya NMN bya Shangke Biopharmaceutical (Shanghai) Co., Ltd. (byitwa "Shangke Bio") byemejwe na Leta Zunze Ubumwe za Amerika. Icyemezo cya FDA NDI cyemeza ko ibikoresho fatizo byayo bya NMN bishobora gukoreshwa ku mugaragaro mu gukora, kugurisha no kwamamaza inyongeramusaruro muri Leta Zunze Ubumwe za Amerika, kandi biboneka ku rubuga rwa interineti rwa FDA nk’ibikoresho fatizo bishya by’inyongeramusaruro, nimero 1247.
FDA NDI ni yo sisitemu y'ingenzi cyane yo kwemeza ibicuruzwa ku isoko rya Amerika. Kubona iyi certification ntibisobanura gusa ko umutekano n'ubuziranenge bw'ibicuruzwa bya Shangke Bio aribyemewe cyane, ariko kandi bifasha iterambere rihoraho ry’inganda za NMN mu gihe kirekire.
| Izina ry'Ubutabire | β-Nicotinamide Mononucleotide |
| Amagambo asa | NICOTINAMIDE-1-IUM-1-BETA-D-RIBOFURANOSIDE 5'-FOSPHATE |
| Nimero ya CAS | 1094-61-7 |
| Uburemere bwa molekile | 334.22 |
| Formula ya Molecular | C11H15N2O8P |
| EINECS 号: | 214-136-5 |
| Aho gushonga | 166 °C (Ukuboza) |
| ubushyuhe bwo kubika. | -20°C |
| gushonga | DMSO (Ishyushye gake), Methanol (Gake), Amazi (Gake) |
| ifishi | Bikomeye |
| ibara | Kuva ku mweru kugeza ku muhondo |
| Merck | 13,6697 |
| BRN | 3570187 |
| Ituze: | Ifite imiterere y'izuba cyane |
| InChIKey | DAYLJWODMCOQEW-TURQNECASA-N |
| Ikintu cy'igerageza | Ibisobanuro |
| Isura | Ifu y'umweru kuva ku ibara ry'umweru kugeza ku ibara ry'umweru |
| Ingano ya sodiyumu | ≤1% |
| Agaciro ka pH (100mg/ml) | 2.0~4.0 |
| Ubwiza | ≥99.0% |
| Ibipimo by'amazi | ≤1% |
| Ibyuma biremereye | <10ppm |
| Arsenic | <0.5ppm |
| Umuyobozi | <0.5ppm |
| Mercure | <0.1ppm |
| Kadimu | <0.5ppm |
| Ibisigazwa by'imiti ishongesha | Ethanol≤1000ppm |
| Umubare wose w'udukoko two mu kirere | <750cfu/g |
| Umusemburo n'Ibihumyo | <25cfu/g |
| Igiteranyo cy'uruhu rw'inyuma | ≤0.92MPN/g |
| E. Coli | Ububi |
| Salmonella | Ububi |
| Staph. Aureus | Ububi |
| Isuzuma (rishingiye ku mazi adafite amazi) | ≥99.0% |
| Igipimo cyo kwibira | ≥95% |
| Ubucucike bw'umubyimba | Raporo kugira ngo ubone amakuru |
Pake:Icupa, agapfunyika ka aluminiyumu, 25kg/Ingoma ya Karito, cyangwa hakurikijwe ibyo umukiriya asabwa.
Imiterere y'ububiko:Bika mu bikoresho bikomeye kandi bidashobora koroha, kugira ngo bibikwe igihe kirekire, bika ahantu hashyushye cyane kuri 2 ~ 8°C cyangwa munsi yayo.
Nicotinamide Mononucleotide (NMN) ni verisiyo nshya ya vitamine B3, ikaba ari intambwe imwe ibanziriza NAD+ (Nicotinamide Adenine Dinucleotide). NMN ni yo mashini ya mbere ya NAD+ igarura uturemangingo yagaragaye ko ikora neza mu kugarura uturemangingo mu mubiri.
Nicotinamide Adenine Dinucleotide (NAD) ni imwe mu ngirabuzimafatizo z'ingenzi kandi zishimishije mu mubiri. Irakenewe ku bikorwa birenga 500 bya enzyme kandi igira uruhare runini mu kugenzura hafi ya byose by'ingenzi mu buzima (Ansari na Raghava, 2010). Ikirenze byose, ishobora gutuma tugira ubuzima bwiza kandi burambye.
Nicotinamide Adenine Dinucleotide (NAD) ibaho mu buryo bwayo bwa oxidized (NAD+) cyangwa mu buryo bwagabanutse (NADH), ibyo bikaba ari ibintu by'ingenzi bigize oxireductases nyinshi.
SyncoZyems, ikigo cya mbere cyabonye ikigo cy’ibikoresho fatizo cyemewe na FDA NDI NMN, gihagarariye ikigo cya FDA cyemera NMN nk’ubwoko bushya bw’ibikoresho bushobora gutangira kwemerwa no kwemerwa nk’ibikoresho by’inyongeramusaruro muri Leta Zunze Ubumwe za Amerika.
