β-Nicotinamide adenine dinucleotide phosphate hydrate (NADP)
SyncoZymes (Shanghai) Co., Ltd. niyo ikora kandi igatanga β-Nicotinamide adenine dinucleotide phosphate hydrate (CAS:53-59-8) ifite ubuziranenge bwo hejuru. Dushobora gutanga COA, itangwa ku isi yose, ingano nto n'inini zirahari. Niba ushishikajwe n'iki gicuruzwa, ohereza amakuru arambuye arimo nimero ya CAS, izina ry'igicuruzwa, n'ingano yacyo. Twandikire:lchen@syncozymes.com
| Izina ry'Ubutabire | β-Nicotinamide adenine dinucleotide fosfeti hydrate |
| Amagambo asa | β-Nicotinamide adenine dinucleotide fosfeti hydrate |
| Nimero ya CAS | 53-59-8 |
| Uburemere bwa molekile | 743.41 |
| Formula ya Molecular | C21H28N7O17P3 |
| EINECS No. | 200-178-1 |
| ubushyuhe bwo kubika. | Bika ahantu hijimye, ahantu hatameze neza, Bika muri firigo, munsi ya -20°C |
| gushonga | H2O: 50 mg/mL, irabagirana, umuhondo muto |
| pka | pKa1 3.9; pKa2 6.1 (kuri 25℃) |
| λmax | 260nm (urumuri) |
| Merck | 14,6348 |
| Sisitemu yo Kwandika Ibiyobyabwenge ya EPA | Adenosine 5'- (trihydrogen diphosphate), 2'- (dihydrogen phosphate), P'.fwdarw.5'-ester hamwe na 3- (aminocarbonyl)-1-.beta.-D-ribofuranosylpyridinium, umunyu w'imbere (53-59-8) |
| Ikintu cy'igerageza | Ibisobanuro |
| Isura | Ifu y'umweru kuva ku muhondo |
| Gushonga | 200mg/ml mu mazi |
| Agaciro ka pH (100mg/ml) | 5.0～7.0 |
| Isesengura rya UV Spectral kuri 260 nm na pH 7.5 | (18±1.0)×10³L/mol/cm |
| Ibikubiye mu bikubiyemo (bikozwe mu isesengura rya enzyme hamwe na G6PDH kuri pH 7.5, hakoreshejwe spectrophotometer, abs.340nm, ku buryo bw'amazi) | ≥90.0% |
| Ubuziranenge (na HPLC, %agace) | ≥95.0% |
| Ingano y'amazi (kuri KF) | ≤5% |
Pake:Icupa, agapfunyika ka aluminiyumu, 25kg/Ingoma ya Karito, cyangwa hakurikijwe ibyo umukiriya asabwa.
Imiterere y'ububiko:Bika ahantu hafunganye neza mu mwijima, kugira ngo bibikwe igihe kirekire, bibike kuri 2 ~ 8°C.
NADP ni coenzyme, ikaba ari ikintu kirimo nicotinamide adenine dinucleotide na molekile ya fosfeti bihuzwa n'umugozi wa ester, kandi bihari cyanemu isi y’ibinyabuzima. Imiterere yayo ya shimi, uburyo bwo kwinjizamo ibintu, imiterere ya redoksi, nibindi bisa na NAD (Coenzyme I). NADP ishobora gukoreshwa cyane mu bikorwa byo gusubiza ibintu mu buryoiterwa imbaraga na dehydrogenase zitandukanye z'inzoga, ketoreductase n'izindi oxidoreductase. Nk'izi: ishobora kugabanuka ikaba NADPH na dehydrogenase nyinshi nkanka 6-phosphoglucose dehydrogenase (EC.1.1.1.49), 6-phosphogluconate dehydrogenase (EC.1.1.1.44). Ariko, ntabwo ari ngombwa ko ishobora kugira ingaruka ku bintu byinshidehydrogenases zikoresha NAD, kandi ntizishobora kongerwamo oxidation mu buryo butaziguye n'uruhererekane rw'ubuhumekero. Bitandukanye na NAD, iba ahanini mu gihe gito mu turemangingo tw'ibinyabuzima bitera aerobic.
Dukurikije uko ibicuruzwa bikoreshwa, bishobora kugabanywamo ibice bikurikira: urwego rwa biotransformation, urwego rwa reagent yo gusuzuma, urwego rw'ibiribwa by'ubuzima.
Icyiciro cya Biotransformation: Ishobora gukoreshwa mu guhuza imiti n'ibice bya API, cyane cyane hifashishijwe enzymes catalytic, nka ketoreductase (KRED),P450 monooxygenase (CYP), formate dehydrogenase (FDH), glucose dehydrogenase (GDH), nibindi. Tegereza.
Icyiciro cy'ibisubizo byo gusuzuma: Ifite imisemburo itandukanye yo gusuzuma, nk'ibikoresho fatizo by'ibikoresho byo gusuzuma.
Icyiciro cy'ibiribwa bizima: Gukoresha inyongeramusaruro za NADP ahanini biri mu bushakashatsi no mu iterambere.
